Cryonics is the low-temperature freezing and storage of human remains, with the speculative hope that resurrection may be possible in the future. Cryonics is regarded with skepticism within the mainstream scientific community. It is generally viewed as a pseudoscience, and its practice has been characterized as quackery.
Neuroscience is the scientific study of the nervous system, its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences.
Cognitive neuroscience is the scientific field that is concerned with the study of the biological processes and aspects that underlie cognition, with a specific focus on the neural connections in the brain which are involved in mental processes. It addresses the questions of how cognitive activities are affected or controlled by neural circuits in the brain. Cognitive neuroscience is a branch of both neuroscience and psychology, overlapping with disciplines such as behavioral neuroscience, cognitive psychology, physiological psychology and affective neuroscience. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neurobiology, and computational modeling.
Mind uploading is a speculative process of whole brain emulation in which a brain scan is used to completely emulate the mental state of the individual in a digital computer. The computer would then run a simulation of the brain's information processing, such that it would respond in essentially the same way as the original brain and experience having a sentient conscious mind.
Eric Richard Kandel is an Austrian-born American medical doctor who specialized in psychiatry, a neuroscientist and a professor of biochemistry and biophysics at the College of Physicians and Surgeons at Columbia University. He was a recipient of the 2000 Nobel Prize in Physiology or Medicine for his research on the physiological basis of memory storage in neurons. He shared the prize with Arvid Carlsson and Paul Greengard.
The Alcor Life Extension Foundation, most often referred to as Alcor, is an American nonprofit, federally tax-exempt, 501(c)(3) organization based in Scottsdale, Arizona, United States. Alcor advocates for, researches, and performs cryonics, the freezing of human corpses and brains in liquid nitrogen after legal death, with hopes of resurrecting and restoring them to full health if the technology to do so becomes available in the future. Cryonics is regarded with skepticism within the scientific community and has been characterized as quackery and pseudoscience.
A time capsule is a historic cache of goods or information, usually intended as a deliberate method of communication with future people, and to help future archaeologists, anthropologists, or historians. The preservation of holy relics dates back for millennia, but the practice of preparing and preserving a collection of everyday artifacts and messages to the future appears to be a more recent practice. Time capsules are sometimes created and buried during celebrations such as a world's fair, a cornerstone laying for a building, or at other ceremonies.
21st Century Medicine (21CM) is a California cryobiological research company which has as its primary focus the development of perfusates and protocols for viable long-term cryopreservation of human organs, tissues and cells at temperatures below −100 °C through the use of vitrification. 21CM was founded in 1993.
In library and archival science, digital preservation is a formal process to ensure that digital information of continuing value remains accessible and usable in the long term. It involves planning, resource allocation, and application of preservation methods and technologies, and combines policies, strategies and actions to ensure access to reformatted and "born-digital" content, regardless of the challenges of media failure and technological change. The goal of digital preservation is the accurate rendering of authenticated content over time.
Thomas K. Donaldson was a mathematician and well-known cryonics advocate. He was born in the state of Kentucky in the United States, and took his Ph.D. from the University of Chicago in 1969. He also lived in Sunnyvale, California, and for many years in Canberra, Australia, where he taught mathematics at Australian National University. He founded both the Cryonics Association of Australia and the Institute for Neural Cryobiology, which has funded ground-breaking research in cryopreservation of brain tissue.
The Terasem Movement is a group of three organizations based in the United States. The name was inspired by Earthseed, a fictional religion from the works of Octavia Butler. The movement was founded by Martine Rothblatt and Bina Aspen Rothblatt, and is guided by principles called the "Truths of Terasem".
The Methuselah Foundation is an American-based global non-profit organization based in Springfield, Virginia, with a declared mission to "make 90 the new 50 by 2030" by supporting tissue engineering and regenerative medicine therapies. The organization was originally incorporated by David Gobel in 2001 as the Performance Prize Society, a name inspired by the British governments Longitude Act, which offered monetary rewards for anyone who could devise a portable, practical solution for determining a ship's longitude.
David Gobel is an American philanthropist, entrepreneur, inventor, and futurist. He is co-founder and CEO of the Methuselah Foundation, CEO of the Methuselah Fund, and one of the first to publicly advance the idea of longevity escape velocity, even before this term was formulated.
Larry Ryan Squire is an American psychiatrist and neuroscientist. He is a professor of psychiatry, neurosciences, and psychology at the University of California, San Diego, and a Senior Research Career Scientist at the Veterans Affairs Medical Center, San Diego. He is a leading investigator of the neurological bases of memory, which he studies using animal models and human patients with memory impairment.
Digital immortality is the hypothetical concept of storing a person's personality in digital substrate, i.e., a computer, robot or cyberspace. The result might look like an avatar behaving, reacting, and thinking like a person on the basis of that person's digital archive. After the death of the individual, this avatar could remain static or continue to learn and self-improve autonomously.
The White House BRAIN Initiative is a collaborative, public-private research initiative announced by the Obama administration on April 2, 2013, with the goal of supporting the development and application of innovative technologies that can create a dynamic understanding of brain function.
Alim Louis Benabid is a French-Algerian emeritus professor, neurosurgeon and member of the French Academy of Sciences, who has had a global impact in the development of deep brain stimulation (DBS) for Parkinson's disease and other movement disorders. He became emeritus professor of biophysics at the Joseph Fourier University in Grenoble in September 2007, and chairman of the board of the Edmond J. Safra Biomedical Research Center in 2009 at Clinatec, a multidisciplinary institute he co-founded in Grenoble that applies nanotechnologies to neurosciences.
Hypothetical technology is technology that does not exist yet, but that could exist in the future. This article presents examples of technologies that have been hypothesized or proposed, but that have not been developed yet. An example of hypothetical technology is teleportation.
Connectome: How the Brain's Wiring Makes Us Who We Are (2012) is a book by Sebastian Seung. It introduces basic concepts in neuroscience and then elaborates on the field of connectomics, i.e., how to scan, decode, compare, and understand patterns in brain connectivity. The book concludes with musings on cryonics and mind uploading. It was selected by The Wall Street Journal as Top Ten Nonfiction of 2012.
Aldehyde-stabilized cryopreservation is a new technique for cryopreservation first demonstrated in 2016 by Robert L. McIntyre and Gregory Fahy at the cryobiology research company 21st Century Medicine, Inc. This technique uses a particular implementation of fixation and vitrification that can successfully preserve a rabbit brain in "near perfect" condition at −135 °C, with the cell membranes, synapses, and intracellular structures intact in electron micrographs. The technique has finally won the Small Animal Brain Preservation Prize of the Brain Preservation Foundation. The cryopreserved brain was rewarmed and no serious degradation was found to have occurred; the brain structure under electron microscopic evaluation after rewarming remained well-preserved. Although this technique has not yet lead to a successful revival of a cryopreserved brain, some researchers see this technique as providing promising directions for future research.
