Brenda A. Schulman | |
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 Schulman in 2005 | |
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| Fields | Biochemistry |
| Institutions | Max Planck Institute of Biochemistry |
| Doctoral advisor | Peter S. Kim |
Brenda Schulman is an American biochemist and structural biologist who is a Director at the Max Planck Institute of Biochemistry, Martinsried, Bavaria. Schulman's research interests focus on a class of proteins known as ubiquitin-like proteins. [1]
Schulman is a native of Tucson, Arizona. [2] Schulman received her bachelor's degree in biology from Johns Hopkins University in 1989 and her PhD in biology from the Massachusetts Institute of Technology in 1996, advised by Peter S. Kim. She then worked as a postdoctoral fellow with Ed Harlow at the Massachusetts General Hospital Cancer Center and later with Nikola Pavletich at the Memorial Sloan Kettering Cancer Center. [1] [2]
Schulman joined the faculty at the St. Jude Children's Research Hospital in 2001 and assumed the Joseph Simone Endowed Chair of Basic Research there in 2014. She became a Howard Hughes Medical Institute Investigator in 2005. She was elected to the American Academy of Arts and Sciences in 2012 and to the National Academy of Sciences in 2014. [1] [2] [3] After sixteen years at St. Jude's, Schulman moved to the Max Planck Institute in 2017. [1]
Schulman's research career has focused on the effects of post-translational modifications on the regulation of proteins in eukaryotic cells. Her work has been particularly influential in characterizing ubiquitin-like proteins (UBLs), a class of proteins that are similar to ubiquitin, such as NEDD8. She has also extensively studied enzymes that for which ubiquitin and UBLs are substrates, particularly the E3 ubiquitin ligases. [4]
Christiane (Janni) Nüsslein-Volhard is a German developmental biologist and a 1995 Nobel Prize in Physiology or Medicine laureate. She is the only woman from Germany to have received a Nobel Prize in the sciences.
Bert Sakmann is a German cell physiologist. He shared the Nobel Prize in Physiology or Medicine with Erwin Neher in 1991 for their work on "the function of single ion channels in cells," and the invention of the patch clamp. Bert Sakmann was Professor at Heidelberg University and is an Emeritus Scientific Member of the Max Planck Institute for Medical Research in Heidelberg, Germany. Since 2008 he leads an emeritus research group at the Max Planck Institute of Neurobiology.
Hartmut Michel is a German biochemist, who received the 1988 Nobel Prize in Chemistry for determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential to photosynthesis.
The Max Planck Institute of Biochemistry is a research institute of the Max Planck Society located in Martinsried, a suburb of Munich. The institute was founded in 1973 by the merger of three formerly independent institutes: the Max Planck Institute of Biochemistry, the Max Planck Institute of Protein and Leather Research, and the Max Planck Institute of Cell Chemistry.
The Max Planck Institute for Biology is a research institute located in Tübingen, Germany, and was formerly known as the Max Planck Institute for Developmental Biology. A predecessor institution operated under the same name from 1948 to 2004.
Matthias Mann is a German physicist and biochemist. He is doing research in the area of mass spectrometry and proteomics.
The Max Planck Institute for Biology Tübingen was located in Tübingen, Germany; it was founded as Max Planck Institute for Virus Research in 1954 as an offshoot of the Tübingen-based Max Planck Institute for Biology. From 1984 to 2021, it was named Max Planck Institute for Developmental Biology. The topics of scientific research conducted at the institute cover a very wide range -- from biochemistry, cell and developmental biology to evolutionary and ecological genetics, functional genomics and bioinformatics -- in order to address fundamental questions in microbial, plant and animal biology, including the interaction between different organisms.
Franz-Ulrich Hartl is a German biochemist and the current Executive Director of the Max Planck Institute of Biochemistry. He is known for his pioneering work in chaperone-mediated protein folding.
Stefan Jentsch was a German cell biologist. He was a director at the Max Planck Institute of Biochemistry in Martinsried, Germany. He is known for his pioneering work in the field of protein modifications by ubiquitin and ubiquitin-like modifiers.
Ivan Đikić is a Croatian-German molecular biologist who is the Director of the Institute of Biochemistry II at Goethe University Frankfurt.
Emmanuelle Marie Charpentier is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing". This was the first science Nobel Prize ever won by two women only.
Ilme Schlichting is a German biophysicist.
Petra Schwille is a German professor and a researcher in the area of biophysics. Since 2011, she has been a director of the Department of Cellular and Molecular Biophysics at the Max Planck Institute for Biochemistry in Martinsried, Germany. She is known for her ground-laying work in the field of fluorescence cross-correlation spectroscopy, and numerous contributions on model membranes. Her current research focuses around bottom-up approaches to building an artificial cell within a broader area of synthetic biology. In 2010, Schwille received the Gottfried Wilhelm Leibniz Prize.
Elena Conti is an Italian biochemist and molecular biologist. She serves as Director and Scientific Member of the Max Planck Institute of Biochemistry in Martinsried, Germany, where she uses structural biology and biophysical techniques to study RNA transport and RNA metabolism. Together with Elisa Izaurralde, she helped characterize proteins important for exporting mRNA out of the nucleus.
Elisa Izaurralde was an Uruguayan biochemist and molecular biologist. She served as Director and Scientific Member of the Department of Biochemistry at the Max Planck Institute for Developmental Biology in Tübingen from 2005 until her death in 2018. In 2008, she was awarded the Gottfried Wilhelm Leibniz Prize, shared with Elena Conti, for "fundamental new insights into intracellular RNA transport and RNA metabolism". Together with Conti, she helped characterize proteins important for exporting mRNA out of the nucleus and later in her career she helped elucidate mechanisms of mRNA silencing, translational repression, and mRNA decay.
Marina V. Rodnina is a German biochemist.
Christine Silberhorn is a German physicist specialising in quantum optics and a full professor at the Paderborn University. In 2011, Silberhorn was awarded the Leibniz Prize and was the youngest recipient of the 2.5 million Euro prize at that time.
Reinhard Jahn is a German biophysicist and neurobiologist known for his studies of cellular membrane fusion. For these investigations, he has been honored with numerous awards, including the 2000 Leibniz Award. Jahn is currently Director at the Max Planck Institute for Biophysical Chemistry and the President of the University of Göttingen in Göttingen, Germany.
Wolfgang P. Baumeister is a German molecular biologist and biophysicist. His research has been pivotal in the development of Cryoelectron tomography.
Alfred "Fred" Wittinghofer is a German biochemist.
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