Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for in silico analyses of biological queries using computational and statistical techniques.
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. Some of this non-coding DNA is non-functional junk DNA, such as pseudogenes, but there is no firm consensus on the total amount of junk DNA.
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of individual genes and their roles in inheritance, genomics aims at the collective characterization and quantification of all of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in genomics have triggered a revolution in discovery-based research and systems biology to facilitate understanding of even the most complex biological systems such as the brain.
Genome Research is a peer-reviewed scientific journal published by Cold Spring Harbor Laboratory Press. Disregarding review journals, Genome Research ranks 2nd in the category 'Genetics and Genomics' after Nature Genetics. The focus of the journal is on research that provides novel insights into the genome biology of all organisms, including advances in genomic medicine. This scope includes genome structure and function, comparative genomics, molecular evolution, genome-scale quantitative and population genetics, proteomics, epigenomics, and systems biology. The journal also features interesting gene discoveries and reports of cutting-edge computational biology and high-throughput biology methodologies. New data in these areas are published as research papers, or methods and resource reports that provide novel information on technologies or tools that will be of interest to a broad readership. The journal was established in 1991 as PCR Methods and Applications and obtained its current title in 1995. According to the Journal Citation Reports, the journal has a 2020 impact factor of 9.043, which peaked in 2014 at 14.630.
PLOS Genetics is a peer-reviewed open access scientific journal established in 2005 and published by the Public Library of Science. The founding editor-in-chief was Wayne N. Frankel. The current editors-in-chief are Gregory S. Barsh and Gregory P. Copenhaver. The journal covers research on all aspects of genetics and genomics.
The TB Structural Genomics Consortium (TBSGC) is a worldwide consortium of scientists developing a foundation for tuberculosis diagnosis and treatment by determining the three-dimensional structures of proteins from M. tuberculosis founded in 2000 as a part of the Protein Structure Initiative. The consortium seeks to solve structures of proteins that are of great interest to the TB biology community. A major goal of the consortium is to have a putative function for every ORF in the TB genome.
Claire M. Fraser is an American genome scientist and microbiologist who has worked in microbial genomics and genome medicine. Her research has contributed to the understanding of the diversity and evolution of microbial life. Fraser is the director of the Institute for Genome Sciences at the University of Maryland School of Medicine in Baltimore, MD, where she holds the Dean's Endowed Professorship in the School of Medicine. She has joint faculty appointments at the University of Maryland School of Medicine in the Departments of Medicine and Microbiology/Immunology. In 2019, she began serving a one-year term as President-Elect for the American Association for the Advancement of Science (AAAS), which will be followed by a one-year term as AAAS president starting in February 2020 and a one-year term as chair of the Board of Directors in February 2021.
The Journal of Vertebrate Paleontology is a bimonthly peer-reviewed scientific journal that was established in 1980 by Jiri Zidek. It covers all aspects of vertebrate paleontology, including vertebrate origins, evolution, functional morphology, taxonomy, biostratigraphy, paleoecology, paleobiogeography, and paleoanthropology. The journal is published by Taylor & Francis on behalf of the Society of Vertebrate Paleontology. According to Journal Citation Reports, the journal has a 2017 impact factor of 2.190.
Nature Genetics is a peer-reviewed scientific journal published by Nature Portfolio. It was established in 1992. It covers research in genetics. The chief editor is Tiago Faial.
Niyaz Ahmed is a molecular epidemiologist, professor of microbial sciences, genomicist, and a veterinarian by training, based in Hyderabad.
Genomics is a peer-reviewed scientific journal in genomics, publishing articles on topics such as comparative genomics, functional genomics, association studies, regulatory DNA elements, and genetics on a genome-wide scale. The journal was established in September 1987.
GeneCards is a database of human genes that provides genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. It is being developed and maintained by the Crown Human Genome Center at the Weizmann Institute of Science, in collaboration with LifeMap Sciences.
The Journal of Human Genetics is a monthly peer-reviewed scientific journal covering all aspects of human genetics and genomics. It was established in 1956 as the Japanese Journal of Human Genetics and was independently published by the Japan Society of Human Genetics. It obtained its current name in 1992. According to the Journal Citation Reports, Journal of Human Genetics has a 2020 impact factor of 3.172.
Functional Ecology is a monthly peer-reviewed scientific journal covering physiological, behavioural, and evolutionary ecology, as well as ecosystems and community ecology, emphasizing an integrative approach.
Rajeev Kumar Varshney is an agricultural scientist, specializing in genomics, genetics, molecular breeding and capacity building in developing countries. Varshney is currently serving as Director, Western Australian State Agricultural Biotechnology Center; Director, Centre for Crop & Food Innovation; and International Chair in Agriculture & Food Security with the Food Futures Institute at Murdoch University, Australia since Feb 2022. Before joining Murdoch University, Australia he served International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), a global agriculture R&D institute, for more than 16 years in different scientific and research leadership roles including Research Program Director for three global research programs– Grain Legumes, Genetic Gains and Accelerated Crop Improvement Program. He has the onus of establishing and nurturing the Center of Excellence in Genomics & Systems Biology (CEGSB), a globally recognized center for genomics research at ICRISAT that made impacts on improving agriculture and development of human resources in several countries including India, China, Kenya, Ethiopia, Tanzania, Nigeria, Ghana, Mali, Senegal, Burkina Faso, etc. Varshney holds Adjunct/Honorary/Visiting Professor positions at 10 academic institutions in Australia, China, Ghana, Hong Kong and India, including The University of Western Australia, University of Queensland, West Africa Centre for Crop Improvement, University of Hyderabad, Chaudhary Charan Singh University and Professor Jayashankar Telangana State Agricultural University.
Reactive & Functional Polymers is a monthly peer-reviewed scientific journal, established in 1982 and published by Elsevier. It covers research on both the science and the technology of reactive polymers including polymers and other polymers with specific chemical reactivity or other functionality. The journal publishes both original research and review papers. The editor-in-chief is Alexander Bismarck.
Usha Vijayraghavan is on the faculty of the Department of Microbiology and Cell Biology, at the Indian Institute of Science. Her major research interests are Molecular Genetics, Plant Development.
Genetics in Medicine is a monthly peer-reviewed medical journal covering medical genetics. It is the official journal of the American College of Medical Genetics and Genomics (ACMG). It was established in 1998 and has been published jointly by Nature Publishing Group on behalf of the ACMG since 2012, though it was originally published by Lippincott Williams & Wilkins. The editor-in-chief is Robert D. Steiner MD.
Shantanu Chowdhury is an Indian structural biologist and a professor at Institute of Genomics and Integrative Biology of the Council of Scientific and Industrial Research. He is known for developing a mechanism for gene regulation mediated by DNA Secondary-Structure in diverse cellular contexts. An elected fellow of the National Academy of Sciences, India, he is a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to biological sciences.
OMICS: A Journal of Integrative Biology is a peer-reviewed scientific journal of omics and integrative biology published by Mary Ann Liebert. The journal was founded in 1995 as Genome Science and Technology, changing its name to Microbial & Comparative Genomics in 1997, eventually acquiring its current title in 2004. The journal is now edited by Vural Özdemir. Since 2008 the journal has been published online only.
