Bromsulfthalein

Bromsulfthalein

Names
Preferred IUPAC name Disodium 3,3′-(4,5,6,7-tetrabromo-3-oxo-2-benzofuran-1,1(3H)-diyl)bis(6-hydroxybenzene-1-sulfonate)
Other names Bromsulphthalein; Bromosulfophthalein; Bromosulphophthalein; BSP; Sulfobromophthalein
Identifiers
CAS Number	71-67-0  Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL453904  N
ChemSpider	6046  Y
ECHA InfoCard	100.005.498
IUPHAR/BPS	4506
PubChem CID	6282
UNII	62E5JU30OV  Y
CompTox Dashboard (EPA)	DTXSID4075378
InChI InChI=1S/C20H10Br4O10S2.2Na/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;/q;2*+1/p-2 Y Key: GHAFORRTMVIXHS-UHFFFAOYSA-L Y InChI=1/C20H10Br4O10S2.2Na/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;/q;2*+1/p-2 Key: GHAFORRTMVIXHS-NUQVWONBAX
SMILES [Na+].[Na+].[O-]S(=O)(=O)c1c(O)ccc(c1)C3(OC(=O)c2c(Br)c(Br)c(Br)c(Br)c23)c4ccc(O)c(c4)S([O-])(=O)=O
Properties
Chemical formula	C20H8Br4Na2O10S2
Molar mass	837.99 g·mol−1
Pharmacology
ATC code	V04CE02 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N  verify  (what is  YN ?) Infobox references

Bromsulfthalein (also known as bromsulphthalein, bromosulfophthalein, and BSP) is a phthalein dye used in liver function tests. Determining the rate of removal of the dye from the blood stream gives a measure of liver function. ^[1] The mechanism by which the liver detoxifies BSP is to attach it to glutathione which is the body’s master antioxidant.

References

1. Rosenthal, Sanford M. (1925). "Clinical Application of the Bromsulphalein Test for Hepatic Function". JAMA: The Journal of the American Medical Association. 84 (15): 1112. doi:10.1001/jama.1925.02660410020008.