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Charles Wyatt Shields IV is an American biomedical engineer and assistant professor at the University of Colorado Boulder in the Department of Chemical and Biological Engineering. [1] His research involves the rational design of colloidal and supracolloidal particles for applications in drug delivery and biosensing. [2]
C. Wyatt Shields IV received a Bachelor of Science with High Distinction in Biomedical Engineering at the University of Virginia graduating in 2011. There he performed undergraduate research with Jeffrey Saucerman and William Walker. [3] He continued his education and research with Gabriel López as a graduate student in Biomedical Engineering at Duke University where he obtained his PhD in 2016. During the attainment of his PhD, Shields studied magnetic and acoustic methods for isolation and analysis of cells. [4]
Shields his continued with postdoctoral research at North Carolina State University where he worked with Orlin Velev and Stefan Zauscher in 2017 [5] and then at Harvard University with Samir Mitragotri in 2018. At Harvard's Wyss Institute, Shields developed cytokine-releasing macrophage "backpacks" that maintain a tumor-killing state in cells, travel to tumor sites, and slow their growth. [6] [7] [8]
Shields became an assistant professor at the University of Colorado Boulder in 2020 in chemical and biological engineering. [8] He is also an affiliate professor in the biomedical engineering program and in the materials science and engineering programs. Working at the intersection of materials, soft matter physics and bioengineering, Shields has focused on understanding how stimuli-responsive particles behave in physiological settings in controlling their assembly and motion for biological applications. [1] His lab has numerous clinical collaborations. [9] Current research includes investigating the role of immune cells in decompression sickness using lung-on-a-chip devices, [10] [11] developing "bottom-up" multifunctional magnetic microrobots, [12] [13] and using acoustically responsive particles for capture and purification of disease biomarkers. [14]
Shields' early career has been highly successful, with numerous high profile awards, 5 patents filed, [15] and over 40 articles published in journals such as Science Advances , [16] [17] Advanced Materials , [18] Advanced Functional Materials , [19] and Journal of Controlled Release . [20] Additionally, he is a Guest Associate Editor for the journal Bioengineering & Translational Medicine.
Shields' career has distinguished itself also for is his commitment to scientific outreach and mentorship. His group for several years, has worked with a local high school to provide engineering problems related to his lab's work in drug delivery and biosensing, permitting students the opportunity to design prototypes and work on real life engineering problems. [21] Shields also has been recognized for his mentorship of students of diverse and underrepresented backgrounds while working under Dr. Gabriel López [22] in 2016.
In his third year at the University of Colorado Boulder, Shields received five distinguished research awards, including a National Science Foundation (NSF) CAREER award, [21] [23] [24] Office of Naval Research (ONR) Young Investigator Program award, [25] Pew Biomedical Scholars award, [26] [27] Packard Fellowship for Science and Engineering, [13] and an NIH National Institute of General Medical Sciences (NIGMS) Maximizing Investigators' Research Award (MIRA). [13] Shields is one of only 20 recipients of the prestigious Packard Fellowship at the University of Colorado Boulder. [28]
Other awards and honors include:
Microbotics is the field of miniature robotics, in particular mobile robots with characteristic dimensions less than 1 mm. The term can also be used for robots capable of handling micrometer size components.
Kristi S. Anseth is the Tisone Distinguished Professor of Chemical and Biological Engineering, an Associate Professor of Surgery, and a Howard Hughes Medical Investigator at the University of Colorado at Boulder. Her main research interests are the design of synthetic biomaterials using hydrogels, tissue engineering, and regenerative medicine.
The Presidential Young Investigator Award(PYI) was awarded by the National Science Foundation of the United States Federal Government. The program operated from 1984 to 1991, and was replaced by the NSF Young Investigator (NYI) Awards and Presidential Faculty Fellows (PFF) program. In 1995, the NSF Young Investigator program was subsumed into the NSF CAREER Awards program, and in 1996, the Presidential Faculty Fellows program was replaced by the PECASE program.
Younan Xia is a Chinese-American chemist, materials scientist, and bioengineer. He is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering, with joint appointments in the School of Chemistry & Biochemistry, the School of Chemical & Biomolecular Engineering, and Parker H. Petit Institute for Bioengineering & Bioscience at the Georgia Institute of Technology.
Samir Mitragotri is an Indian American professor at Harvard University, an inventor, an entrepreneur, and a researcher in the fields of drug delivery and biomaterials. He is currently the Hiller Professor of Bioengineering and Hansjörg Wyss Professor of Biologically Inspired Engineering at Harvard John A. Paulson School of Engineering and Applied Sciences and the Wyss Institute for Biologically Inspired Engineering. Prior to 2017, he was the Duncan and Suzanne Mellichamp Chair Professor at University of California, Santa Barbara.
Jillian Lee Dempsey is an American inorganic chemist and the Bowman and Gordon Gray Distinguished Term Professor at the University of North Carolina at Chapel Hill. Currently, her work focuses on proton-coupled electron transfer, charge transfer events, and quantum dots. She is the recipient of numerous awards for rising stars of chemistry, including most recently a 2016 Alfred P. Sloan Research Fellowship and a 2016 Air Force's Young Investigator Research Program (YIP).
Tan Weihong is a Chinese chemist. He is the University of Florida Distinguished Professor, V. T. and Louise Jackson Professor of Chemistry at the University of Florida, and also the Professor of Chemistry and Chemical Engineering, Professor of Biology, and Director of the State Key Laboratory of Chemo/Biosensing and Chemometrics at Hunan University in China. He was elected an academician of the Chinese Academy of Sciences in 2015 and The World Academy of Sciences in 2016.
Orlin D. Velev is the INVISTA Professor in the Department of Chemical and Biomolecular Engineering at North Carolina State University. He is best known for his work in soft matter, colloid science, and nanoscience.
Jessica O. Winter is an American bioengineer. She is a Professor of Chemical, Biomolecular, and Biomedical Engineering and an Associate Director of the MRSEC Center for Emergent Materials at the Ohio State University. Her research interests include nanoparticles for cancer imaging, diagnostics, and drug delivery; and cell migration in the brain tumor microenvironment. In 2021, she was elected a fellow of the American Association for the Advancement of Science, American Institute for Medical and Biological Engineering, Biomedical Engineering Society, and Royal Society of Chemistry.
John X. J. Zhang is a tenured professor at Thayer School of Engineering of Dartmouth College, and an investigator in the Dartmouth-Hitchcock Medical Center. Before joining Dartmouth, he was an associate professor with tenure in the Department of Biomedical Engineering at the University of Texas(UT Austin). He received his Ph.D. in electrical engineering from Stanford University, California in 2004, and was a research scientist in systems biology at the Massachusetts Institute of Technology (MIT) before joining the faculty at UT Austin in 2005. Zhang is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE), and a recipient of the 2016 NIH Director's Transformative Research Award.
Elizabeth Wayne is an Assistant Professor of Biomedical Engineering and Chemical Engineering at Carnegie Mellon University and former Postdoc at the Center for Nanotechnology in Drug Delivery at the University of North Carolina at Chapel Hill. Wayne was a 2017 TED fellow and is a member of a number of professional societies, including the National Society of Black Physicists.
Omolola (Lola) Eniola-Adefeso is a Nigerian-American chemical engineer and the University Diversity and Social Transformation Professor of Chemical Engineering, Biomedical Engineering, and Macromolecular Science and Engineering at the University of Michigan. Eniola-Adefeso is also a co-founder and chief scientific officer of Asalyxa Bio. Her research looks to design biocompatible functional particles for targeted drug delivery.
Guillermo Antonio Ameer is the Daniel Hale Williams Professor of biomedical engineering at the Robert R. McCormick School of Engineering and Applied Science and Surgery at the Feinberg School of Medicine of Northwestern University and is a fellow of the American Institute for Medical and Biological Engineering, Biomedical Engineering Society, American Institute of Chemical Engineers, American Association for the Advancement of Science, Materials Research Society, and American Academy of Arts and Sciences. He is an engineer, inventor, and entrepreneur.
Kimberly A. Prather is an American atmospheric chemist. She is a distinguished chair in atmospheric chemistry and a distinguished professor at the Scripps Institution of Oceanography and department of chemistry and biochemistry at UC San Diego. Her work focuses on how humans are influencing the atmosphere and climate. In 2019, she was elected a member of the National Academy of Engineering for technologies that transformed understanding of aerosols and their impacts on air quality, climate, and human health. In 2020, she was elected as a member of the National Academy of Sciences. She is also an elected Fellow of the American Philosophical Society, American Geophysical Union, the American Association for the Advancement of Science, American Philosophical Society, and the American Academy of Arts and Sciences.
Jerome Schultz is an American bioengineering researcher, professor, and university administrator. He is a fellow of several national scientific societies and a member of the National Academy of Engineering. He has held professorships at the University of Michigan, the University of Pittsburgh, University of California, Riverside, and he is currently a Distinguished Professor of Biomedical Engineering at the University of Houston.
The Department of Defense National Defense Science and Engineering Graduate Fellowship is a prestigious fellowship awarded annually to U.S. citizens pursuing doctoral degrees in science and engineering disciplines. The highly competitive fellowship is sponsored by the U.S. Navy, U.S. Space Force, U.S. Air Force, and U.S. Army. These agencies make the final selection of the fellows. National Defense Fellows must be enrolled in research-based doctoral degrees aligned with the goals of the U.S. Department of Defense as outlined in a specific solicitation for research proposals, known as a Broad Agency Announcement (BAA). Qualifying doctoral programs must be based in the United States. The NDSEG Fellowship lasts for three years, paying for full tuition and all mandatory fees in that period. The fellowship also awards the recipient a monthly stipend, totaling $40,800 annually, a $5,000 travel budget for the 3-year tenure, and a $1,400 annual health insurance budget. National Defense Fellows have no military service obligation upon completion of the program. In the 2020-2021 award cycle, 159 fellows were chosen from a pool of over 7,942 applicants, for a selection rate of roughly 2%.
Stacey Finley is the Nichole A. and Thuan Q. Pham Professor and associate professor of chemical engineering and materials science, and quantitative and computational biology at the University of Southern California. Finley has a joint appointment in the department of chemical engineering and materials science, and she is a member of the USC Norris Comprehensive Cancer Center. Finley is also a standing member of the MABS Study Section at NIH. Her research has been supported by grants from the NSF, NIH, and American Cancer Society.
Chenzhong Li is a Chinese-born Canadian & American biomedical engineer, chemist, inventor, professor, and journal editor. Li is the co-Editor-in-Chief of the journal Biosensors and Bioelectronics (Elsevier) and the associate editors of journals RESEARCH (AAAS) and Biosensors (MDPI).
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