CAMK1D

CAMK1D
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JC6
Identifiers
Aliases	CAMK1D , CKLiK, CaM-K1, CaMKID, calcium/calmodulin dependent protein kinase ID
External IDs	OMIM: 607957; MGI: 2442190; HomoloGene: 121858; GeneCards: CAMK1D; OMA:CAMK1D - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	12,835,545 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	5,719,326 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; parietal lobe; ; postcentral gyrus; ; Brodmann area 23; ; cerebellar vermis; ; superior frontal gyrus; ; entorhinal cortex; ; nipple; ; primary visual cortex; ; trigeminal ganglion;
	Top expressed in
	olfactory tubercle; ; piriform cortex; ; primary motor cortex; ; medial geniculate nucleus; ; retinal pigment epithelium; ; dentate gyrus; ; subdivision of hippocampus; ; Region I of hippocampus proper; ; amygdala; ; anterior amygdaloid area;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity ; nucleotide binding ; protein kinase activity ; kinase activity ; protein serine/threonine kinase activity ; catalytic activity ; ATP binding ; calmodulin-dependent protein kinase activity ; calmodulin binding ;
Cellular component	nucleus ; cytoplasm ;
Biological process	regulation of granulocyte chemotaxis ; positive regulation of phagocytosis ; phosphorylation ; negative regulation of apoptotic process ; regulation of dendrite development ; nervous system development ; protein phosphorylation ; positive regulation of CREB transcription factor activity ; positive regulation of apoptotic process ; metabolism ; inflammatory response ; positive regulation of respiratory burst ; positive regulation of neutrophil chemotaxis ; positive regulation of neuron projection development ; peptidyl-serine phosphorylation ; peptidyl-threonine phosphorylation ; intracellular signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	57118
	227541
	ENSG00000183049
	ENSMUSG00000039145
	Q8IU85
	Q8BW96
	NM_020397 ; NM_153498 ; NM_001351032
	NM_001290374 ; NM_001290375 ; NM_001290376 ; NM_177343
	NP_065130 ; NP_705718 ; NP_001337961
	NP_001277303 ; NP_001277304 ; NP_001277305 ; NP_796317
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 09, 2024

Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10 (locus 10p13).^[5]

Function

This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded protein may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

External links

Human CAMK1D genome location and CAMK1D gene details page in the UCSC Genome Browser .
Overview of all the structural information available in the PDB for UniProt : Q8IU85 (Human Calcium/calmodulin-dependent protein kinase type 1D (CAMK1D)) at the PDBe-KB .

Related Research Articles

Inositol-trisphosphate 3-kinase B is an enzyme that in humans is encoded by the ITPKB gene.

Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIα), a.k.a.Ca²⁺/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene.

Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene.

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.

Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene.

Calcium/calmodulin-dependent protein kinase type 1 is an enzyme that in humans is encoded by the CAMK1 gene.

Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene.

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A is an enzyme that in humans is encoded by the PDE1A gene.

Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene.

Death-associated protein kinase 2 is an enzyme that in humans is encoded by the DAPK2 gene.

Cyclin-dependent kinase 5 activator 2 is an enzyme that in humans is encoded by the CDK5R2 gene.

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene. Alternative splicing results in multiple transcript variants.

Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.

Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene.

Calcium channel, voltage-dependent, T type, alpha 1I subunit, also known as CACNA1I or Ca_v3.3 is a protein which in humans is encoded by the CACNA1I gene.

Myosin light chain kinase 2 also known as MYLK2 is an enzyme which in humans is encoded by the MYLK2 gene.

Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.

Calpain-6 is a protein in humans that is encoded by the CAPN6 gene.

Calcium/calmodulin dependent protein kinase II inhibitor 1 is a protein that in humans is encoded by the CAMK2N1 gene.

Calcium/calmodulin dependent protein kinase IG is a protein that in humans is encoded by the CAMK1G gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000183049 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039145 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Calcium/calmodulin-dependent protein kinase ID".

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000183049 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039145 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Calcium/calmodulin-dependent protein kinase ID".

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CAMK1D

Contents

Function

External links

Related Research Articles

References