CBX8

Last updated

CBX8
Protein CBX8 PDB 2dnv.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CBX8 , PC3, RC1, chromobox 8
External IDs OMIM: 617354; MGI: 1353589; HomoloGene: 32199; GeneCards: CBX8; OMA:CBX8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020649

NM_013926

RefSeq (protein)

NP_065700

NP_038954

Location (UCSC) Chr 17: 79.79 – 79.8 Mb Chr 11: 118.93 – 118.93 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene. [5] [6]

Contents


Interactions

CBX8 has been shown to interact with RING1 [7] and MLLT1. [8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141570 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025578 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bardos JI, Saurin AJ, Tissot C, Duprez E, Freemont PS (Oct 2000). "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties". J Biol Chem. 275 (37): 28785–92. doi: 10.1074/jbc.M001835200 . PMID   10825164.
  6. "Entrez Gene: CBX8 chromobox homolog 8 (Pc class homolog, Drosophila)".
  7. Bárdos JI, Saurin A J, Tissot C, Duprez E, Freemont P S (Sep 2000). "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties". J. Biol. Chem. 275 (37): 28785–92. doi: 10.1074/jbc.M001835200 . ISSN   0021-9258. PMID   10825164.
  8. García-Cuéllar MP, Zilles O, Schreiner S A, Birke M, Winkler T H, Slany R K (Jan 2001). "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3". Oncogene. 20 (4): 411–9. doi: 10.1038/sj.onc.1204108 . ISSN   0950-9232. PMID   11313972.

Further reading