MLLT1

Last updated
MLLT1
Identifiers
Aliases MLLT1 , ENL, LTG19, YEATS1, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1, super elongation complex subunit, MLLT1 super elongation complex subunit
External IDs OMIM: 159556 MGI: 1927238 HomoloGene: 4339 GeneCards: MLLT1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005934

NM_022328

RefSeq (protein)

NP_005925

NP_071723

Location (UCSC) Chr 19: 6.21 – 6.28 Mb Chr 17: 57.2 – 57.24 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein ENL is a protein that in humans is encoded by the MLLT1 gene. [5]

Contents


Interactions

MLLT1 has been shown to interact with CBX8. [6]

Related Research Articles

<span class="mw-page-title-main">BCR (gene)</span>

The breakpoint cluster region protein (BCR) also known as renal carcinoma antigen NY-REN-26 is a protein that in humans is encoded by the BCR gene. BCR is one of the two genes in the BCR-ABL fusion protein, which is associated with the Philadelphia chromosome. Two transcript variants encoding different isoforms have been found for this gene.

<span class="mw-page-title-main">Zinc finger and BTB domain-containing protein 16</span> Protein found in humans

Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.

<span class="mw-page-title-main">HOXA9</span> Protein-coding gene in humans

Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene.

<span class="mw-page-title-main">KMT2A</span> Protein-coding gene in the species Homo sapiens

Histone-lysine N-methyltransferase 2A, also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia1 (MLL1), or zinc finger protein HRX (HRX), is an enzyme that in humans is encoded by the KMT2A gene.

<span class="mw-page-title-main">RUNX1T1</span> Protein-coding gene in humans

Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene.

<span class="mw-page-title-main">Protein SET</span> Protein-coding gene in the species Homo sapiens

Protein SET, also known as Protein SET 1, is a protein that in humans is encoded by the SET gene.

<span class="mw-page-title-main">DEK (gene)</span> Protein-coding gene in the species Homo sapiens

The human DEKgene encodes the DEK protein.

<i>ERG</i> (gene) Protein-coding gene in the species Homo sapiens

ERG is an oncogene. ERG is a member of the ETS family of transcription factors. The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. Genes in the ETS family regulate embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis.

<span class="mw-page-title-main">AFF1</span> Protein-coding gene in the species Homo sapiens

AF4/FMR2 family member 1 is a protein that in humans is encoded by the AFF1 gene. At its same location was a record for a separate PBM1 gene, which has since been withdrawn and considered an alias. It was previously known as AF4.

<span class="mw-page-title-main">ELL (gene)</span> Protein-coding gene in the species Homo sapiens

RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene.

<i>HLF</i> (gene) Protein-coding gene in the species Homo sapiens

Hepatic leukemia factor is a protein that in humans is encoded by the HLF gene.

<span class="mw-page-title-main">MLLT10</span> Protein-coding gene in the species Homo sapiens

Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.

<span class="mw-page-title-main">LYL1</span> Protein-coding gene in the species Homo sapiens

Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.

<span class="mw-page-title-main">MLLT3</span> Protein-coding gene in the species Homo sapiens

Protein AF-9 is a protein that in humans is encoded by the MLLT3 gene.

<span class="mw-page-title-main">ASH2L</span> Protein-coding gene in the species Homo sapiens

Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene.

<span class="mw-page-title-main">PBX3</span> Protein found in humans

Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene.

<span class="mw-page-title-main">RBBP5</span> Protein-coding gene in the species Homo sapiens

Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene.

<span class="mw-page-title-main">CBX8</span> Protein-coding gene in the species Homo sapiens

Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.

<span class="mw-page-title-main">Tet methylcytosine dioxygenase 1</span> Mammalian protein found in Homo sapiens

Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function, regulation, and utilizable pathways remain a matter of current research while it seems to be involved in DNA demethylation and therefore gene regulation.

<span class="mw-page-title-main">KMT2E</span> Protein-coding gene in the species Homo sapiens

Lysine methyltransferase 2E is a protein that in humans is encoded by the KMT2E gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000130382 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024212 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1".
  6. García-Cuéllar MP, Zilles O, Schreiner SA, Birke M, Winkler TH, Slany RK (January 2001). "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3". Oncogene. 20 (4): 411–9. doi: 10.1038/sj.onc.1204108 . PMID   11313972.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.