MLLT1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | MLLT1 , ENL, LTG19, YEATS1, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1, super elongation complex subunit, MLLT1 super elongation complex subunit | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 159556 MGI: 1927238 HomoloGene: 4339 GeneCards: MLLT1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Protein ENL is a protein that in humans is encoded by the MLLT1 gene. [5]
The breakpoint cluster region protein (BCR) also known as renal carcinoma antigen NY-REN-26 is a protein that in humans is encoded by the BCR gene. BCR is one of the two genes in the BCR-ABL fusion protein, which is associated with the Philadelphia chromosome. Two transcript variants encoding different isoforms have been found for this gene.
Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.
Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene.
Histone-lysine N-methyltransferase 2A, also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia1 (MLL1), or zinc finger protein HRX (HRX), is an enzyme that in humans is encoded by the KMT2A gene.
Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene.
Protein SET, also known as Protein SET 1, is a protein that in humans is encoded by the SET gene.
The human DEKgene encodes the DEK protein.
ERG is an oncogene. ERG is a member of the ETS family of transcription factors. The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. Genes in the ETS family regulate embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis.
AF4/FMR2 family member 1 is a protein that in humans is encoded by the AFF1 gene. At its same location was a record for a separate PBM1 gene, which has since been withdrawn and considered an alias. It was previously known as AF4.
RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene.
Hepatic leukemia factor is a protein that in humans is encoded by the HLF gene.
Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.
Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.
Protein AF-9 is a protein that in humans is encoded by the MLLT3 gene.
Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene.
Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene.
Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene.
Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.
Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function, regulation, and utilizable pathways remain a matter of current research while it seems to be involved in DNA demethylation and therefore gene regulation.
Lysine methyltransferase 2E is a protein that in humans is encoded by the KMT2E gene.
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: CS1 maint: unflagged free DOI (link)This article incorporates text from the United States National Library of Medicine, which is in the public domain.