ZNF644

ZNF644
Identifiers
Aliases	ZNF644 , BM-005, MYP21, NatF, ZEP-2, zinc finger protein 644
External IDs	OMIM: 614159 MGI: 1277212 HomoloGene: 12971 GeneCards: ZNF644
Gene location (Human)
Chr.	Chromosome 1 (human)
End	91,022,272 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	106,697,287 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ganglionic eminence; ; tibialis anterior muscle; ; corpus callosum; ; bone marrow cells; ; pancreatic epithelial cell; ; deltoid muscle; ; endothelial cell; ; sural nerve; ; lactiferous duct;
	Top expressed in
	spermatocyte; ; spermatid; ; medial ganglionic eminence; ; extensor digitorum longus muscle; ; maxillary prominence; ; cingulate gyrus; ; atrium; ; cerebellar vermis; ; olfactory epithelium; ; molar;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding ; metal ion binding ; nucleic acid binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ; DNA-binding transcription factor activity ;
Cellular component	nucleus ;
Biological process	regulation of transcription, DNA-templated ; transcription, DNA-templated ; regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	84146
	52397
	ENSG00000122482
	ENSMUSG00000049606
	Q9H582
	n/a
	NM_016620 ; NM_032186 ; NM_201269
NM_026856 ; NM_001363318 ; NM_001363319 ; NM_001363320 ; NM_001363321 ;
	NM_001363322 ; NM_001363323
	NP_057704 ; NP_115562 ; NP_958357
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 28, 2023

Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a protein that in humans is encoded by the ZNF644 gene.^[5]

Clinical relevance

Mutations in the ZNF644 gene have been found in sporadic cases of high myopia.^[6]

Related Research Articles

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Zinc finger and BTB domain-containing protein 20 is a protein that in humans is encoded by the ZBTB20 gene.

Zinc finger protein 330 is a protein that in humans is encoded by the ZNF330 gene.

Zinc finger protein 7 is a protein that in humans is encoded by the ZNF7 gene.

Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.

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Zinc finger protein 687 is a zinc finger protein that, in humans, is encoded by the ZNF687 gene.

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Zinc finger protein 436 is a protein that in humans is encoded by the ZNF436 gene.

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Sal-like protein 3, also known as zinc finger protein SALL3, is a protein that in humans in encoded by the SALL3 gene.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122482 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049606 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: zinc finger protein 644".
↑ Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLOS Genetics. 7 (6): e1002084. doi: 10.1371/journal.pgen.1002084 . PMC 3111487 . PMID 21695231.

Zabaneh D, Balding DJ (2010). "A genome-wide association study of the metabolic syndrome in Indian Asian men". PLOS ONE. 5 (8): e11961. Bibcode:2010PLoSO...511961Z. doi: 10.1371/journal.pone.0011961 . PMC 2915922 . PMID 20694148.
Mulligan P, Westbrook TF, Ottinger M, et al. (2008). "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation". Mol. Cell. 32 (5): 718–26. doi:10.1016/j.molcel.2008.10.025. PMC 6595072 . PMID 19061646.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID 16710414.
Zhang QH, Ye M, Wu XY, et al. (2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000122482 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049606 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: zinc finger protein 644".

[6] Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLOS Genetics. 7 (6): e1002084. doi: 10.1371/journal.pgen.1002084 . PMC 3111487 . PMID 21695231.

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ZNF644

Contents

Clinical relevance

Related Research Articles

References

Further reading