ZNF259

ZPR1
Identifiers
Aliases	ZPR1 , ZNF259, ZPR1 zinc finger
External IDs	OMIM: 603901 MGI: 1330262 HomoloGene: 2900 GeneCards: ZPR1
Gene location (Human)
Chr.	Chromosome 11 (human) [1]
End	116,788,039 bp [1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse) [2]
End	46,282,643 bp [2]
Gene ontology
Molecular function	• receptor tyrosine kinase binding ; • zinc ion binding ; • metal ion binding ; • GO:0001948 protein binding ; • translation initiation factor binding ;
Cellular component	• cytoplasm ; • perikaryon ; • Cajal body ; • cell projection ; • growth cone ; • nucleoplasm ; • SMN complex ; • axon ; • neuronal cell body ; • nucleolus ; • perinuclear region of cytoplasm ; • cell nucleus ; • Gemini of coiled bodies ;
Biological process	• cell differentiation ; • axon development ; • pre-mRNA catabolic process ; • Cajal body organization ; • mRNA processing ; • apoptotic process involved in development ; • positive regulation of growth ; • inner cell mass cell proliferation ; • cellular response to epidermal growth factor stimulus ; • positive regulation of gene expression ; • regulation of myelination ; • positive regulation of transcription involved in G1/S transition of mitotic cell cycle ; • RNA splicing ; • spinal cord development ; • positive regulation of RNA splicing ; • positive regulation of protein import into nucleus ; • cellular proliferation ; • DNA endoreduplication ; • microtubule cytoskeleton organization ; • trophectodermal cell proliferation ; • signal transduction ; • negative regulation of motor neuron apoptotic process ;
	Sources:Amigo / QuickGO
Orthologs
	8882
	22687
	ENSG00000109917
	ENSMUSG00000032078
	O75312
	Q62384
	NM_003904 ; NM_001317086
	NM_011752
	NP_001304015 ; NP_003895
	NP_035882
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 17, 2020

Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.^[5]^[6]^[7]

Related Research Articles

Zinc finger protein 148 is a protein that in humans is encoded by the ZNF148 gene.

Cellular nucleic acid-binding protein is a protein that in humans is encoded by the CNBP gene.

Zinc finger protein 350 is a protein that in humans is encoded by the ZNF350 gene.

Zinc finger protein OZF is a protein that in humans is encoded by the ZNF146 gene.

Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene.

Zinc finger protein 217, also known as ZNF217, is a protein which in humans is encoded by the ZNF217 gene.

Zinc finger protein 238 is a zinc finger containing transcription factor that in humans is encoded by the ZNF238 gene.

Zinc finger protein 10 is a protein that in humans is encoded by the ZNF10 gene.

Zinc finger protein 24 is a protein that in humans is encoded by the ZNF24 gene.

Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.

Zinc finger and BTB domain-containing protein 32 is a protein that in humans is encoded by the 1960 bp ZBTB32 gene. The 52 kDa protein is a transcriptional repressor and the gene is expressed in T and B cells upon activation, but also significantly in testis cells. It is a member of the Poxviruses and Zinc-finger (POZ) and Krüppel (POK) family of proteins, and was identified in multiple screens involving either immune cell tumorigenesis or immune cell development.

Zinc finger protein 267 is a protein that in humans is encoded by the ZNF267 gene.

Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.

Zinc finger protein 330 is a protein that in humans is encoded by the ZNF330 gene.

Zinc finger protein 19 is a protein that in humans is encoded by the ZNF19 gene.

Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.

Zinc finger protein 34 is a protein that in humans is encoded by the ZNF34 gene.

Zinc finger protein 423 is a protein that in humans is encoded by the ZNF423 gene.

Zinc finger protein 184, also known as ZNF184, is a protein that in humans is encoded by the ZNF184 gene on chromosome 6. It was first identified by Goldwurm et al. in 1996.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000109917 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032078 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (June 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor". Science. 272 (5269): 1797–802. doi:10.1126/science.272.5269.1797. PMID 8650580.
↑ Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (October 1998). "The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells". Molecular Biology of the Cell. 9 (10): 2963–71. doi:10.1091/mbc.9.10.2963. PMC 25573 . PMID 9763455.
↑ "Entrez Gene: ZNF259 zinc finger protein 259".

External links

ZNF259+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000109917 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032078 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8650580-5] Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (June 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor". Science. 272 (5269): 1797–802. doi:10.1126/science.272.5269.1797. PMID 8650580.

[pmid9763455-6] Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (October 1998). "The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells". Molecular Biology of the Cell. 9 (10): 2963–71. doi:10.1091/mbc.9.10.2963. PMC 25573 . PMID 9763455.

[entrez-7] "Entrez Gene: ZNF259 zinc finger protein 259".

ZNF259

Contents

Related Research Articles

References

Further reading

External links