POU3F1

Last updated
POU3F1
Identifiers
Aliases POU3F1 , OCT6, OTF6, SCIP, POU class 3 homeobox 1
External IDs OMIM: 602479 HomoloGene: 135923 GeneCards: POU3F1
Orthologs
SpeciesHumanMouse
Entrez

5453

n/a

Ensembl

ENSG00000185668

n/a

UniProt

Q03052

n/a

RefSeq (mRNA)

NM_002699

n/a

RefSeq (protein)

NP_002690

n/a

Location (UCSC) Chr 1: 38.04 – 38.05 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene. [3] [4]

Contents

See also

Related Research Articles

Oct-4 Mammalian protein found in Homo sapiens

Oct-4, also known as POU5F1, is a protein that in humans is encoded by the POU5F1 gene. Oct-4 is a homeodomain transcription factor of the POU family. It is critically involved in the self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.

Homeobox protein NANOG Transcriptional factor that helps embryonic stem cells (ESCs) maintain pluripotency by suppressing cell determination factors

Homeobox protein NANOG is a transcriptional factor that helps embryonic stem cells (ESCs) maintain pluripotency by suppressing cell determination factors. Several types of cancer are associated with NANOG.

Pituitary-specific positive transcription factor 1 Protein-coding gene in the species Homo sapiens

POU domain, class 1, transcription factor 1 , also known as POU1F1, is a transcription factor for growth hormone.

Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain.

Oct-2 also known as POU domain, class 2, transcription factor 2 is a protein that in humans is encoded by the POU2F2 gene.

HNF1A Protein-coding gene in the species Homo sapiens

HNF1 homeobox A, also known as HNF1A, is a human gene on chromosome 12. It is ubiquitously expressed in many tissues and cell types. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. Mutations in the HNF1A gene have been known to cause diabetes. The HNF1A gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.

HMGA1 Protein-coding gene in the species Homo sapiens

High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.

POU2F1 Protein-coding gene in the species Homo sapiens

POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.

Non-POU domain-containing octamer-binding protein Protein-coding gene in the species Homo sapiens

Non-POU domain-containing octamer-binding protein (NonO) is a protein that in humans is encoded by the NONO gene.

POU is a family of proteins that have well-conserved homeodomains.

HMGB2 Protein-coding gene in the species Homo sapiens

High-mobility group protein B2 also known as high-mobility group protein 2 (HMG-2) is a protein that in humans is encoded by the HMGB2 gene.

POU2AF1

POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. The protein is also termed Oct coactivator from B cells, Oct binding factor 1, and, as commonly found in the literature, BOB1. BOB1 is a transcriptional coactivator which is expressed principally by B-cell lymphocytes and controls immunoglobulin and other genes critical for these cells expression of CD20, CRISP-3, and CD36. The expression of BOB1 has proven useful for identifying certain lymphomas as being B-cell lymphomas, as exemplified in studies which use BAB1 expression to help identify lymphomas as being diffuse large B-cell lymphomas, not otherwise specified.

SLC22A1

Solute carrier family 22 member 1 is a protein that in humans is encoded by the gene SLC22A1.

POU3F2 Protein-coding gene in the species Homo sapiens

POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene.

POU4F1 Protein-coding gene in the species Homo sapiens

POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene.

POU4F2 Protein-coding gene in the species Homo sapiens

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.

ELF5

E74-like factor 5 , is a gene found in both mice and humans. In humans it is also called ESE2.

POU2F3

POU domain, class 2, transcription factor 3 is a protein that in humans is encoded by the POU2F3 gene.

POU3F4 Protein-coding gene in the species Homo sapiens

POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome.

POU4F3 Protein-coding gene in the species Homo sapiens

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185668 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ↑ Tobler A, Schreiber E, Fontana A (Feb 1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart". Nucleic Acids Research. 21 (4): 1043. doi:10.1093/nar/21.4.1043. PMC   309249 . PMID   8451175.
  4. ↑ "Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.