FOXJ2

FOXJ2
Identifiers
Aliases	FOXJ2 , FHX, forkhead box J2
External IDs	MGI: 1926805 HomoloGene: 10187 GeneCards: FOXJ2
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12p13.31 Start 8,032,716 bp [1] End 8,055,517 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 F2 Start 122,796,873 bp [2] End 122,822,325 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in nipple saphenous vein cardia vena cava body of tongue thoracic diaphragm superior surface of tongue pylorus pericardium urethra Top expressed in ankle inner renal medulla thin ascending limb of loop of Henle triceps brachii muscle extraocular muscle vastus lateralis muscle temporal muscle ciliary body ascending aorta digastric muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific protein binding identical protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus fibrillar center Biological process positive regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II anatomical structure morphogenesis cell differentiation negative regulation of angiogenesis negative regulation of blood vessel endothelial cell differentiation positive regulation of vascular associated smooth muscle cell proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55810 60611 Ensembl ENSG00000065970 ENSMUSG00000003154 UniProt Q9P0K8 Q9ES18 RefSeq (mRNA) NM_018416 NM_021899 RefSeq (protein) NP_060886 NP_068699 Location (UCSC) Chr 12: 8.03 – 8.06 Mb Chr 6: 122.8 – 122.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Forkhead box protein J2 is a protein that in humans is encoded by the FOXJ2 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000065970 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000003154 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Perez-Sanchez C, Gomez-Ferreria MA, de La Fuente CA, Granadino B, Velasco G, Esteban-Gamboa A, Rey-Campos J (Jun 2000). "FHX, a novel fork head factor with a dual DNA binding specificity". J Biol Chem. 275 (17): 12909–16. doi: 10.1074/jbc.275.17.12909 . hdl: 10261/168715 . PMID   10777590.
6. Perez-Sanchez C, Arias-de-la-Fuente C, Gomez-Ferreria MA, Granadino B, Rey-Campos J (Sep 2000). "FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity". J Mol Biol. 301 (4): 795–806. doi:10.1006/jmbi.2000.3999. PMID   10966786.
7. "Entrez Gene: FOXJ2 forkhead box J2".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gómez-Ferrería MA, Rey-Campos J (2003). "Functional domains of FOXJ2". J. Mol. Biol. 329 (4): 631–44. doi:10.1016/S0022-2836(03)00524-2. PMID   12787665.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.