GTF3C2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | GTF3C2 , TFIIIC-BETA, TFIIIC110, general transcription factor IIIC subunit 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604883 MGI: 1919002 HomoloGene: 37490 GeneCards: GTF3C2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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General transcription factor 3C polypeptide 2 is a protein that in humans is encoded by the GTF3C2 gene. [5] [6]
GTF3C2 has been shown to interact with GTF3C4 [7] and GTF3C5. [8]
Robert G. Roeder is an American biochemist. He is known as a pioneer scientist in eukaryotic transcription. He discovered three distinct nuclear RNA polymerases in 1969 and characterized many proteins involved in the regulation of transcription, including basic transcription factors and the first mammalian gene-specific activator over five decades of research. He is the recipient of the Gairdner Foundation International Award in 2000, the Albert Lasker Award for Basic Medical Research in 2003, and the Kyoto Prize in 2021. He currently serves as Arnold and Mabel Beckman Professor and Head of the Laboratory of Biochemical and Molecular Biology at The Rockefeller University.
The TATA-binding protein (TBP) is a general transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters.
Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a complex composed of the TATA binding protein TBP and TBP-associated factors (TAFs), as well as the factors TFIIB, TFIIE, TFIIF, and TFIIH. Together, these factors are responsible for promoter recognition and the formation of a transcription preinitiation complex (PIC) capable of initiating RNA synthesis from a DNA template.
Transcription initiation factor TFIID subunit 6 is a protein that in humans is encoded by the TAF6 gene.
Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene.
General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.
Transcription initiation factor TFIID subunit 5 is a protein that in humans is encoded by the TAF5 gene.
Transcription factor IIIB 90 kDa subunit is a protein that in humans is encoded by the BRF1 gene.
Transcription initiation factor TFIID subunit 11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene.
General transcription factor IIH subunit 2 is a protein that in humans is encoded by the GTF2H2 gene.
General transcription factor 3C polypeptide 1 is a protein that in humans is encoded by the GTF3C1 gene.
Transcription initiation factor TFIID subunit 13 is a protein that in humans is encoded by the TAF13 gene.
Transcription factor TFIIIB component B″ homolog also known as TFIIIB150 is a protein that in humans is encoded by the BDP1 gene.
DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the POLR3F gene.
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.
General transcription factor IIF subunit 2 is a protein that in humans is encoded by the GTF2F2 gene.
DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene.
Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is encoded by the BRF2 gene.
General transcription factor 3C polypeptide 5 is a protein that in humans is encoded by the GTF3C5 gene.
General transcription factor 3C polypeptide 4 is a protein that in humans is encoded by the GTF3C4 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.