HIVEP1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | HIVEP1 , CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A, human immunodeficiency virus type I enhancer binding protein 1, HIVEP zinc finger 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 194540 MGI: 96100 HomoloGene: 1596 GeneCards: HIVEP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Zinc finger protein 40 is a protein that in humans is encoded by the HIVEP1 gene. [5] [6]
Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM] [6]
Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene.
Importin subunit alpha-1 is a protein that in humans is encoded by the KPNA1 gene.
Transcription factor RelB is a protein that in humans is encoded by the RELB gene.
The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel is a myeloid checkpoint protein that can be targeted for treating cancer. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin's lymphoma.
DNA-directed RNA polymerase II subunit RPB9 is an enzyme that in humans is encoded by the POLR2I gene.
Importin subunit alpha-3 is a protein that in humans is encoded by the KPNA4 gene.
Importin subunit alpha-7 is a protein that in humans is encoded by the KPNA6 gene.
C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299.
Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene.
HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene.
E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene.
Importin-7 is a protein that in humans is encoded by the IPO7 gene.
Zinc finger and BTB domain-containing protein 7A is a protein that in humans is encoded by the ZBTB7A gene.
Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.
Transcription factor HIVEP2 is a protein that in humans is encoded by the HIVEP2 gene.
NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene.
Glycoprotein endo-alpha-1,2-mannosidase is an enzyme that in humans is encoded by the MANEA gene.
Transcription factor HIVEP3 is a protein that in humans is encoded by the HIVEP3 gene.
GBA2 is the gene that encodes the enzyme non-lysosomal glucosylceramidase in humans. It has glucosylceramidase activity.
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB is an enzyme that in humans is encoded by the MAN1A2 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.