Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene. [5]
Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene. [5]
Expression of interleukin-3 (IL-3) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site. [5] [6]
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit signals from a receptor complex to the nucleus and activate gene expression. Similarly as other STAT family proteins, STAT6 is also activated by growth factors and cytokines. STAT6 is mainly activated by cytokines interleukin-4 and interleukin-13.
CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.
Nuclear factor of activated T-cells, cytoplasmic 2 is a protein that in humans is encoded by the NFATC2 gene.
The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel is a myeloid checkpoint protein that can be targeted for treating cancer. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin's lymphoma.
Neurogenic differentiation 1 (Neurod1), also called β2, is a transcription factor of the NeuroD-type. It is encoded by the human gene NEUROD1.
Cyclic AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene.
Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. MEF2C is a transcription factor in the Mef2 family.
Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the PBX1 gene. The homologous protein in Drosophila is known as extradenticle, and causes changes in embryonic development.
Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.
Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene.
Ribosomal protein S6 kinase alpha-1 is an enzyme that in humans is encoded by the RPS6KA1 gene.
Host cell factor 1, also known as VP16-accessory protein, is a protein that in humans is encoded by the HCFC1 gene.
General transcription factor II-I is a protein that in humans is encoded by the GTF2I gene.
Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene.
Hepatic leukemia factor is a protein that in humans is encoded by the HLF gene.
Transcription initiation protein SPT3 homolog is a protein that in humans is encoded by the SUPT3H gene.
Transcription factor GATA-5 is a protein that in humans is encoded by the GATA5 gene.
ETS-related transcription factor Elf-4 is a protein that in humans is encoded by the ELF4 gene.
E74-like factor 1 is a protein that in humans is encoded by the ELF1 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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