HOXD11 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | HOXD11 , HOX4, HOX4F, homeobox D11 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 142986; MGI: 96203; HomoloGene: 7368; GeneCards: HOXD11; OMA:HOXD11 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Homeobox protein Hox-D11 is a protein that in humans is encoded by the HOXD11 gene. [5] [6] [7]
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in axial skeleton development and forelimb morphogenesis. [7] [8] [9] [10]
Homeobox D10, also known as HOXD10, is a protein which in humans is encoded by the HOXD10 gene.
Homeobox protein Hox-C8 is a protein that in humans is encoded by the HOXC8 gene.
Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.
Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene.
Homeobox protein Hox-A13 is a protein that in humans is encoded by the HOXA13 gene.
Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene.
Homeobox protein Hox-D3 is a protein that in humans is encoded by the HOXD3 gene.
Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.
Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. Hox-C6 expression is highest in the fallopian tube and ovary. HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.
Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene.
Homeobox protein Hox-D4 is a protein that in humans is encoded by the HOXD4 gene.
Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.
Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene.
Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene.
Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.
Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene.
Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.
Homeobox protein Hox-C10 is a protein that in humans is encoded by the HOXC10 gene.
Homeobox protein Hox-C11 is a protein that in humans is encoded by the HOXC11 gene.
Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.
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: CS1 maint: DOI inactive as of August 2024 (link)This article incorporates text from the United States National Library of Medicine, which is in the public domain.