TOX2

Last updated
TOX high mobility group box family member 2
Identifiers
SymbolTOX2
Alt. symbolsC20orf100, GCX-1
NCBI gene 84969
HGNC 16095
OMIM 611163
RefSeq NM_001098796
UniProt Q96NM4
Other data
Locus Chr. 20 q13.12
Search for
Structures Swiss-model
Domains InterPro

TOX high mobility group box family member 2, also known as TOX2, is a human gene. [1] [2]

The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure. [3]

References

  1. ↑ "Entrez Gene: TOX high mobility group box family member 2".
  2. ↑ Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K (May 2004). "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology. 145 (5): 2307–18. doi:10.1210/en.2003-1343. PMID   14764631. S2CID   25037508.
  3. ↑ O'Flaherty E, Kaye J (April 2003). "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics. 4 (1) 13. doi: 10.1186/1471-2164-4-13 . PMC   155677 . PMID   12697058.


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.