| ZNF74 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | ZNF74 , COS52, ZFP520, ZNF520, hZNF7, zinc finger protein 74 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 194548 HomoloGene: 88675 GeneCards: ZNF74 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Zinc finger protein 74 is a protein that in humans is encoded by the ZNF74 gene. [3] [4] [5] Schizophrenia susceptibility has been associated with a mutation in this protein. [6]
The Krüppel associated box (KRAB) domain is a category of transcriptional repression domains present in approximately 400 human zinc finger protein-based transcription factors. The KRAB domain typically consists of about 75 amino acid residues, while the minimal repression module is approximately 45 amino acid residues. It is predicted to function through protein-protein interactions via two amphipathic helices. The most prominent interacting protein is called TRIM28 initially visualized as SMP1, cloned as KAP1 and TIF1-beta. Substitutions for the conserved residues abolish repression.
DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans.
C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene. CtBP1 is one of two CtBP proteins, the other protein being CtBP2.
Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene.
Tristetraprolin (TTP), also known as zinc finger protein 36 homolog (ZFP36), is a protein that in humans, mice and rats is encoded by the ZFP36 gene. It is a member of the TIS11 family, along with butyrate response factors 1 and 2.
Zyxin is a protein that in humans is encoded by the ZYX gene.
PDZ and LIM domain protein 5 is a protein that in humans is encoded by the PDLIM5 gene.
Serine/threonine-protein kinase N2 is an enzyme that in humans and Strongylocentrotus purpuratus is encoded by the PKN2 gene.
Ubiquitin-conjugating enzyme E2 D1 is a protein that in humans is encoded by the UBE2D1 gene.
Chimerin 2 (beta-chimaerin) is a protein that in humans is encoded by the CHN2 gene.
Paired mesoderm homeobox protein 2A is a protein that in humans is encoded by the PHOX2A gene.
Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.
AP-3 complex subunit sigma-2 is a protein that in humans is encoded by the AP3S2 gene.
Myeloid zinc finger 1 is a protein that in humans is encoded by the MZF1 gene.
POZ-, AT hook-, and zinc finger-containing protein 1 is a protein that in humans is encoded by the PATZ1 gene.
Zinc finger protein 10 is a protein that in humans is encoded by the ZNF10 gene.
Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.
Zinc finger protein 7 is a protein that in humans is encoded by the ZNF7 gene.
Zinc finger protein 268 is a protein that in humans is encoded by the ZNF268 gene. ZNF268 is associated with cervical cancer.
Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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