TLX2

Last updated
TLX2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TLX2 , HOX11L1, NCX, T-cell leukemia homeobox 2, T cell leukemia homeobox 2
External IDs OMIM: 604240 MGI: 1350935 HomoloGene: 7575 GeneCards: TLX2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016170
NM_001534

NM_009392

RefSeq (protein)

NP_057254

NP_033418

Location (UCSC) Chr 2: 74.51 – 74.52 Mb Chr 6: 83.05 – 83.05 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene. [5] [6]

Contents

Interactions

TLX2 has been shown to interact with YWHAH. [7]

Related Research Articles

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<span class="mw-page-title-main">HIPK2</span> Protein-coding gene in the species Homo sapiens

Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene. HIPK2 can be categorized as a Serine/Threonine Protein kinase, specifically one that interacts with homeodomain transcription factors. It belongs to a family of protein kinases known as the DYRK kinases. Within this family HIPK2 belongs to a group of homeodomain-interacting protein kinases (HIPKs), including HIPK1 and HIPK3. HIPK2 can be found in a wide variety of species and its functions in gene expression and apoptosis are regulated by several different mechanisms.

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<span class="mw-page-title-main">NK2 homeobox 1</span> Mammalian protein found in Homo sapiens

NK2 homeobox 1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene.

<span class="mw-page-title-main">Homeobox protein Nkx-2.5</span> Protein-coding gene in humans

Homeobox protein Nkx-2.5 is a protein that in humans is encoded by the NKX2-5 gene.

<span class="mw-page-title-main">Homeobox A1</span> Protein-coding gene in humans

Homeobox protein Hox-A1 is a protein that in humans is encoded by the HOXA1 gene.

<span class="mw-page-title-main">MEIS1</span> Protein-coding gene in humans

Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene.

<span class="mw-page-title-main">HOXA5</span> Protein-coding gene in humans

Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.

<span class="mw-page-title-main">HHEX</span> Protein-coding gene in the species Homo sapiens

Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene and also known as Proline Rich Homeodomain protein PRH.

<span class="mw-page-title-main">HOXB2</span> Protein-coding gene in humans

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.

<span class="mw-page-title-main">HOXB9</span> Protein-coding gene in humans

Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene.

<i>NRL</i> (gene) Protein-coding gene in the species Homo sapiens

Neural retina-specific leucine zipper protein is a protein that in humans is encoded by the NRL gene.

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Homeobox protein Hox-C4 is a protein that in humans is encoded by the HOXC4 gene.

<span class="mw-page-title-main">PBX2</span> Protein found in humans

Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene.

<span class="mw-page-title-main">ORC5</span> Protein-coding gene in the species Homo sapiens

Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene.

<span class="mw-page-title-main">HOXD4</span> Protein-coding gene

Homeobox protein Hox-D4 is a protein that in humans is encoded by the HOXD4 gene.

<span class="mw-page-title-main">HOXC13</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.

<i>EN1</i> (gene) Protein-coding gene in the species Homo sapiens

Homeobox protein engrailed-1 is a protein that in humans is encoded by the EN1 gene.

<span class="mw-page-title-main">HIPK1</span> Protein-coding gene in the species Homo sapiens

Homeodomain-interacting protein kinase 1 is an enzyme that, in humans is encoded by the HIPK1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000115297 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068327 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Puliti A, Cinti R, Betsos N, Romeo G, Ceccherini I (Jun 1999). "HOX11L1, a gene involved in peripheral nervous system development, maps to human chromosome 2p13.1→p12 and mouse chromosome 6C3-D1". Cytogenetics and Cell Genetics. 84 (1–2): 115–7. doi:10.1159/000015234. PMID   10343123. S2CID   21498122.
  6. "Entrez Gene: TLX2 T-cell leukemia homeobox 2".
  7. Tang SJ, Suen TC, McInnes RR, Buchwald M (September 1998). "Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins". The Journal of Biological Chemistry. 273 (39): 25356–63. doi: 10.1074/jbc.273.39.25356 . PMID   9738002.

Further reading