ZNF318

ZNF318
Identifiers
Aliases	ZNF318 , TZF, ZFP318, HRIHFB2436, zinc finger protein 318
External IDs	OMIM: 617512; MGI: 1889348; HomoloGene: 22808; GeneCards: ZNF318; OMA:ZNF318 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p21.1 Start 43,307,134 bp [1] End 43,369,647 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 C Start 46,694,657 bp [2] End 46,731,846 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis testicle right hemisphere of cerebellum gonad granulocyte secondary oocyte apex of heart lymph node sural nerve Top expressed in tail of embryo saccule genital tubercle secondary oocyte zygote neural layer of retina otic vesicle testicle spermatocyte mesenteric lymph nodes More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding nucleic acid binding protein homodimerization activity Cellular component nucleus nucleoplasm cytosol Biological process regulation of transcription, DNA-templated meiosis transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 24149 57908 Ensembl ENSG00000171467 ENSMUSG00000015597 UniProt Q5VUA4 Q99PP2 RefSeq (mRNA) NM_014345 NM_021346 NM_207671 RefSeq (protein) NP_055160 NP_067321 NP_997554 Location (UCSC) Chr 6: 43.31 – 43.37 Mb Chr 17: 46.69 – 46.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 318 is a zinc finger protein that in humans is encoded by the ZNF318 gene. ^{[5] [6]} It has a role in the promotion of immunoglobulin D expression and in controlling the alternative splicing of the long pre-mRNA. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000171467 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000015597 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Inoue A, Ishiji A, Kasagi S, Ishizuka M, Hirose S, Baba T, et al. (Jul 2000). "The transcript for a novel protein with a zinc finger motif is expressed at specific stages of mouse spermatogenesis". Biochemical and Biophysical Research Communications. 273 (2): 398–403. doi:10.1006/bbrc.2000.2953. PMID   10873617.
6. "Entrez Gene: ZNF318 zinc finger protein 318".
7. Murphy, K, Weaver, C (2016). Janeway's Immunobiology. New York, NY: Garland Science/Taylor and Francis. p. 195. ISBN   978-0-8153-4505-3.

Further reading

• Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (Dec 1998). "Selection system for genes encoding nuclear-targeted proteins". Nature Biotechnology. 16 (13): 1338–1342. doi:10.1038/4315. PMID   9853615. S2CID   20001769.
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, et al. (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–12135. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Ishizuka M, Kawate H, Takayanagi R, Ohshima H, Tao RH, Hagiwara H (Jun 2005). "A zinc finger protein TZF is a novel corepressor of androgen receptor". Biochemical and Biophysical Research Communications. 331 (4): 1025–1031. doi:10.1016/j.bbrc.2005.04.024. PMID   15882980.
• Tao RH, Kawate H, Ohnaka K, Ishizuka M, Hagiwara H, Takayanagi R (Mar 2006). "Opposite effects of alternative TZF spliced variants on androgen receptor". Biochemical and Biophysical Research Communications. 341 (2): 515–521. doi:10.1016/j.bbrc.2005.12.213. PMID   16446156.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.

External links

• ZNF318+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.