Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. [5] [6] [7]
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [7]
Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the PBX1 gene. The homologous protein in Drosophila is known as extradenticle, and causes changes in embryonic development.
Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.
Homeobox D10, also known as HOXD10, is a protein which in humans is encoded by the HOXD10 gene.
Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.
Homeobox protein Hox-B4 is a protein that in humans is encoded by the HOXB4 gene.
Homeobox protein Hox-C8 is a protein that in humans is encoded by the HOXC8 gene.
Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.
PBX/Knotted 1 Homeobox 1 (PKNOX1) is a protein that in humans is encoded by the PKNOX1 gene.
Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.
Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene.
Homeobox protein Hox-D3 is a protein that in humans is encoded by the HOXD3 gene.
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Homeobox protein Hox-C4 is a protein that in humans is encoded by the HOXC4 gene.
Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.
Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene.
Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. Hox-C6 expression is highest in the fallopian tube and ovary. HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.
Homeobox protein Hox-D4 is a protein that in humans is encoded by the HOXD4 gene.
Homeobox protein Hox-B8 is a protein that in humans is encoded by the HOXB8 gene.
Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene.
PBX/Knotted 1 Homeobox 2 (PKNOX2) protein belongs to the three amino acid loop extension (TALE) class of homeodomain proteins, and is encoded by PKNOX2 gene in humans. The protein regulates the transcription of other genes and affects anatomical development.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.