Related Research Articles
A homeobox is a DNA sequence, around 180 base pairs long, found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi, plants, and numerous single cell eukaryotes. Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can cause developmental disorders.
EGR-1 also known as ZNF268 or NGFI-A is a protein that in humans is encoded by the EGR1 gene.
POU domain, class 1, transcription factor 1 , also known as POU1F1, is a transcription factor for growth hormone.
Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain.
POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.
HNF1 homeobox B, also known as HNF1B or transcription factor 2 (TCF2), is a human gene.
POU is a family of proteins that have well-conserved homeodomains.
POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene.
POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene.
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Homeobox protein Hox-C4 is a protein that in humans is encoded by the HOXC4 gene.
Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.
Paired related homeobox 1 is a protein that in humans is encoded by the PRRX1 gene.
POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.
POU domain, class 3, transcription factor 1 is a protein that in humans is encoded by the POU3F1 gene.
Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.
Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene.
POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome.
LIM/homeobox protein Lhx4 is a protein that in humans is encoded by the LHX4 gene.
POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene. It's a member of BRN-3 group, also known as POU family class 4.
References
- ↑ Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB, Nathans J (1995). "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. doi: 10.1523/JNEUROSCI.15-07-04762.1995 . PMC 6577904 . PMID 7623109.
