HOXD9

Last updated
HOXD9
Protein HOXD9 PDB 1puf.png
Identifiers
Aliases HOXD9 , HOX4, HOX4C, Hox-4.3, Hox-5.2, homeobox D9
External IDs OMIM: 142982; MGI: 96210; HomoloGene: 8409; GeneCards: HOXD9; OMA:HOXD9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014213

NM_013555

RefSeq (protein)

NP_055028

NP_038583

Location (UCSC) Chr 2: 176.12 – 176.12 Mb Chr 2: 74.53 – 74.53 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene. [5] [6] [7]

Contents

Function

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [7]

See also

Related Research Articles

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Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

<span class="mw-page-title-main">HOXD10</span> Protein-coding gene in humans

Homeobox D10, also known as HOXD10, is a protein which in humans is encoded by the HOXD10 gene.

<span class="mw-page-title-main">HOXB5</span> Protein-coding gene in humans

Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.

<span class="mw-page-title-main">HOXC8</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C8 is a protein that in humans is encoded by the HOXC8 gene.

<span class="mw-page-title-main">HOXD13</span> Protein

Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.

<span class="mw-page-title-main">HOXB1</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene.

<span class="mw-page-title-main">HOXB2</span> Protein-coding gene in humans

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.

<span class="mw-page-title-main">HOXD3</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-D3 is a protein that in humans is encoded by the HOXD3 gene.

<span class="mw-page-title-main">HOXB3</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.

<span class="mw-page-title-main">HOXC4</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C4 is a protein that in humans is encoded by the HOXC4 gene.

<span class="mw-page-title-main">HOXC6</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. Hox-C6 expression is highest in the fallopian tube and ovary. HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.

<span class="mw-page-title-main">HOXD4</span> Protein-coding gene

Homeobox protein Hox-D4 is a protein that in humans is encoded by the HOXD4 gene.

<span class="mw-page-title-main">HOXD11</span> Protein-coding gene in humans

Homeobox protein Hox-D11 is a protein that in humans is encoded by the HOXD11 gene.

<span class="mw-page-title-main">HOXC13</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.

<span class="mw-page-title-main">HOXD12</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene.

<span class="mw-page-title-main">HOXC9</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene.

<span class="mw-page-title-main">HOXD1</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.

<span class="mw-page-title-main">HOXC5</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene.

<span class="mw-page-title-main">HOXD8</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.

<span class="mw-page-title-main">HOXC11</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-C11 is a protein that in humans is encoded by the HOXC11 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000128709 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000043342 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID   1973146.
  6. Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID   1358459. S2CID   13370372.
  7. 1 2 "Entrez Gene: HOXD9 homeobox D9".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.