ZNF217 | |||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | ZNF217 , ZABC1, zinc finger protein 217 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602967 MGI: 2685408 HomoloGene: 4757 GeneCards: ZNF217 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
|
Zinc finger protein 217, also known as ZNF217, is a protein which in humans is encoded by the ZNF217 gene. [5] [6]
ZNF217 can attenuate apoptotic signals resulting from telomere dysfunction and may promote neoplastic transformation and later stages of malignancy. [7] Znf217 was shown to be a prognostic biomarker and therapeutic target during breast cancer progression. [8]
Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from human glioblastoma cells.
Krueppel-like factor 6 is a protein that in humans is encoded by the KLF6 gene.
Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene.
Nuclear receptor coactivator 6 is a protein that in humans is encoded by the NCOA6 gene.
Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene. It is important normal hematopoiesis.
Zinc finger protein 350 is a protein that in humans is encoded by the ZNF350 gene.
Zinc finger protein OZF is a protein that in humans is encoded by the ZNF146 gene.
Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene.
Zinc finger protein 202 is a transcription factor first associated with breast cancer. It is a protein that, in humans, is encoded by the ZNF202 gene.
Zinc finger protein 238 is a zinc finger containing transcription factor that in humans is encoded by the ZNF238 gene.
Breast carcinoma-amplified sequence 1 is a protein that in humans is encoded by the BCAS1 gene.
Zinc finger and BTB domain-containing protein 32 is a protein that in humans is encoded by the 1960 bp ZBTB32 gene. The 52 kDa protein is a transcriptional repressor and the gene is expressed in T and B cells upon activation, but also significantly in testis cells. It is a member of the Poxviruses and Zinc-finger (POZ) and Krüppel (POK) family of proteins, and was identified in multiple screens involving either immune cell tumorigenesis or immune cell development.
Zinc finger and BTB domain-containing protein 21 is a protein that in humans is encoded by the ZBTB21 gene.
Transcriptional-regulating factor 1 is a protein that in humans is encoded by the TRERF1 gene.
Transmembrane prostate androgen-induced protein is a protein that in humans is encoded by the PMEPA1 gene.
Zinc finger protein 267 is a protein that in humans is encoded by the ZNF267 gene.
Zinc finger protein 366, also known as DC-SCRIPT, is a protein that in humans is encoded by the ZNF366 gene. The ZNF366 gene was first identified in a DNA comparison study between 85 kb of Fugu rubripes sequence containing 17 genes with its homologous loci in the human draft genome.
Breast carcinoma amplified sequence 3, also known as BCAS3, is a protein which in humans is encoded by the BCAS3 gene. BCAS3 is a gene that is amplified and overexpressed in breast cancer cells.
ZNF703 is a gene which has been linked with the development of breast cancers. ZNF703 is contained within the NET/N1z family responsible for regulation of transcription essential for developmental growth especially in the hindbrain. Normal functions performed by ZNF703 include adhesion, movement and proliferation of cells. ZNF703 directly accumulates histone deacetylases at gene promoter regions but does not bind to functional DNA.
Zinc finger and BTB domain containing 48 (ZBTB48), also known as telomeric zinc-finger associated protein (TZAP), is a protein that directly binds to the double-stranded repeat sequence of telomeres. In humans it is encoded by the ZBTB48 gene.