KLF17

KLF17
Identifiers
Aliases	KLF17 , ZNF393, Zfp393, Kruppel-like factor 17, Kruppel like factor 17, ZLF393
External IDs	OMIM: 609602 MGI: 2181068 HomoloGene: 12621 GeneCards: KLF17
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p34.1 Start 44,118,821 bp [1] End 44,135,140 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4 D1|4 53.46 cM Start 117,615,033 bp [2] End 117,622,845 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in smooth muscle tissue sperm stromal cell of endometrium right lung left adrenal gland right adrenal gland urinary bladder myometrium gallbladder appendix Top expressed in secondary oocyte spermatid urethra male urethra morula seminiferous tubule detrusor urinae muscle spermatocyte right ventricle triceps brachii muscle More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific Cellular component nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 128209 75753 Ensembl ENSG00000171872 ENSMUSG00000048626 UniProt Q5JT82 Q8CFA7 RefSeq (mRNA) NM_173484 NM_029416 RefSeq (protein) NP_775755 NP_083692 Location (UCSC) Chr 1: 44.12 – 44.14 Mb Chr 4: 117.62 – 117.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000171872 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048626 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. van Vliet J, Crofts LA, Quinlan KG, Czolij R, Perkins AC, Crossley M (Apr 2006). "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. doi:10.1016/j.ygeno.2005.12.011. PMID   16460907.
6. "Entrez Gene: KLF17 Kruppel-like factor 17".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Yan W, Burns KH, Ma L, Matzuk MM (Oct 2002). "Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein". Mechanisms of Development. 118 (1–2): 233–9. doi:10.1016/S0925-4773(02)00258-7. PMID   12351194. S2CID   16603729.

External links

• KLF17 protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)