PRRX2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | PRRX2 , PMX2, PRX2, paired related homeobox 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604675 MGI: 98218 HomoloGene: 7524 GeneCards: PRRX2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Paired mesoderm homeobox protein 2 is a protein that in humans is encoded by the PRRX2 gene. [5] [6]
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [6]
Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene.
Homeobox protein DLX-4 is a protein that in humans is encoded by the DLX4 gene.
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Homeobox A4, also known as HOXA4, is a protein which in humans is encoded by the HOXA4 gene.
T-cell leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene.
Paired related homeobox 1 is a protein that in humans is encoded by the PRRX1 gene.
Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.
Visual system homeobox 1 is a protein that in humans is encoded by the VSX1 gene.
Homeobox protein Hox-C11 is a protein that in humans is encoded by the HOXC11 gene.
Homeobox protein Meis2 is a protein that in humans is encoded by the MEIS2 gene.
Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene.
Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.
Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene.
E74-like factor 2 (ELF2), formerly known as new Ets-related factor (NERF), is an ETS family transcription factor. In humans this protein is encoded by the ELF2 gene.
Rhox homeobox family member 1 is a protein that in humans is encoded by the RHOXF1 gene.
Homeobox protein SIX4 is a protein that in humans is encoded by the SIX4 gene.
Homeobox protein SIX2 is a protein that in humans is encoded by the SIX2 gene.
Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.
Iroquois-class homeodomain protein IRX-6, also known as Iroquois homeobox protein 6, is a protein that in humans is encoded by the IRX6 gene.
Short-stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.