KLF12 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | KLF12 , AP-2rep, AP2REP, HSPC122, Kruppel-like factor 12, Kruppel like factor 12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 607531 MGI: 1333796 HomoloGene: 21417 GeneCards: KLF12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Krueppel-like factor 12 is a protein that in humans is encoded by the KLF12 gene. [5] [6]
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [6]
In molecular genetics, the Krüppel-like family of transcription factors (KLFs) are a set of eukaryotic C2H2 zinc finger DNA-binding proteins that regulate gene expression. This family has been expanded to also include the Sp transcription factor and related proteins, forming the Sp/KLF family.
Krueppel-like factor 6 is a protein that in humans is encoded by the KLF6 gene.
Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1, is a protein that in humans is encoded by the TRIM28 gene.
C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene. CtBP1 is one of two CtBP proteins, the other protein being CtBP2.
Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19. It is in the Krüppel-like factor family of zinc finger transcription factors, and it has been implicated in a variety of biochemical processes in the human body, including lung development, embryonic erythropoiesis, epithelial integrity, T-cell viability, and adipogenesis.
C-terminal-binding protein 2 also known as CtBP2 is a protein that in humans is encoded by the CTBP2 gene.
Dr1-associated corepressor is a protein that in humans is encoded by the DRAP1 gene.
Krueppel-like factor 10 is a protein that in humans is encoded by the KLF10 gene.
Krueppel-like factor 11 is a protein that in humans is encoded by the KLF11 gene.
Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene.
Zinc finger protein 350 is a protein that in humans is encoded by the ZNF350 gene.
Zinc finger protein 274 is a protein that in humans is encoded by the ZNF274 gene.
Zinc finger protein 161 homolog is a protein that in humans is encoded by the ZFP161 gene.
Krüppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene.
Zinc finger protein 41 is a protein that in humans is encoded by the ZNF41 gene.
Zinc finger protein 224 is a protein that in humans is encoded by the ZNF224 gene.
Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a protein which in humans is encoded by the KLF7 gene.
Zinc finger protein 160 is a protein that, in humans, is encoded by the ZNF160 gene.
Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene. The corresponding Klf14 mouse gene is known as Sp6.
Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family. Its former designation KKLF stands for kidney-enriched Krüppel-like factor.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.