Chicken ovalbumin upstream promoter-transcription factor

Last updated
nuclear receptor subfamily 2, group F, member 1
Identifiers
SymbolNR2F1
Alt. symbolsERBAL3, TFCOUP1, EAR-3, COUP-TFI, TCFCOUP1, SVP44
NCBI gene 7025
HGNC 7975
OMIM 132890
RefSeq NM_005654
UniProt P10589
Other data
Locus Chr. 5 q14
nuclear receptor subfamily 2, group F, member 2
Identifiers
SymbolNR2F2
Alt. symbolsARP1, TFCOUP2, COUP-TFII, COUPTFB, SVP40
NCBI gene 7026
HGNC 7976
OMIM 107773
RefSeq NM_021005
UniProt P24468
Other data
Locus Chr. 15 q26

The chicken ovalbumin upstream promoter transcription factor (COUP-TFs) proteins are members of the nuclear receptor family of intracellular transcription factors. [1] There are two variants of the COUP-TFs, labeled as COUP-TFI and COUP-TFII encoded by the NR2F1 and NR2F2 genes respectively.

COUP-TFs play critical roles in the development of organisms. [2]

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References

  1. Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY (1995). "Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes". Genomics. 29 (1): 240–6. doi:10.1006/geno.1995.1237. PMID   8530078.
  2. Park JI, Tsai SY, Tsai MJ (2003). "Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions" (PDF). The Keio Journal of Medicine. 52 (3): 174–81. doi: 10.2302/kjm.52.174 . PMID   14529150.