Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene. [5] [6]
Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene. [5] [6]
Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM] [6]
Nuclear factor of activated T-cells, cytoplasmic 2 is a protein that in humans is encoded by the NFATC2 gene.
Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene.
Nuclear transcription factor Y subunit beta is a protein that in humans is encoded by the NFYB gene.
GA-binding protein alpha chain is a protein that in humans is encoded by the GABPA gene.
Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene.
COUP-TF1 also known as NR2F1 is a protein that in humans is encoded by the NR2F1 gene. This protein is a member of nuclear hormone receptor family of steroid hormone receptors.
Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene.
Transcriptional regulator Kaiso is a protein that in humans is encoded by the ZBTB33 gene. This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2, which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene.
Lysine-specific demethylase 5A is an enzyme that in humans is encoded by the KDM5A gene.
Nuclear factor 1 C-type is a protein that in humans is encoded by the NFIC gene.
DNA-binding protein A is a protein that in humans is encoded by the CSDA gene.
Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates Glial fibrillary acidic protein and YKL-40 in astrocytes.
Zinc finger and BTB domain-containing protein 7A is a protein that in humans is encoded by the ZBTB7A gene.
Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.
Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.
Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is encoded by the BRF2 gene.
Transcription elongation factor A protein-like 1 is a protein that in humans is encoded by the TCEAL1 gene.
Nuclear factor 1 B-type is a protein that in humans is encoded by the NFIB gene.
PBX/Knotted 1 Homeobox 2 (PKNOX2) protein belongs to the three amino acid loop extension (TALE) class of homeodomain proteins, and is encoded by PKNOX2 gene in humans. The protein regulates the transcription of other genes and affects anatomical development.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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