CCDC28B

CCDC28B
Identifiers
Aliases	CCDC28B , coiled-coil domain containing 28B
External IDs	OMIM: 610162; MGI: 1913514; HomoloGene: 11509; GeneCards: CCDC28B; OMA:CCDC28B - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p35.2 Start 32,200,595 bp [1] End 32,205,453 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 D2.2 Start 129,513,067 bp [2] End 129,517,740 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle triceps brachii muscle right uterine tube Skeletal muscle tissue of rectus abdominis right testis left testis vastus lateralis muscle anterior pituitary apex of heart Top expressed in neural layer of retina cerebellar cortex lobe of cerebellum cerebellar vermis lip neural tube dentate gyrus of hippocampal formation granule cell sternocleidomastoid muscle temporal muscle granulocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm centrosome cytoskeleton microtubule organizing center Biological process cell projection organization cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79140 66264 Ensembl ENSG00000160050 ENSMUSG00000028795 UniProt Q9BUN5 Q8CEG5 RefSeq (mRNA) NM_001301011 NM_024296 NM_025455 RefSeq (protein) NP_001287940 NP_077272 NP_079731 Location (UCSC) Chr 1: 32.2 – 32.21 Mb Chr 4: 129.51 – 129.52 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Coiled-coil domain-containing protein 28B is a protein that in humans is encoded by the CCDC28B gene. ^{[5] [6]}

The product of this gene localizes to centrosomes and basal bodies. It interacts and colocalizes with several proteins associated with Bardet–Biedl syndrome (BBS). ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000160050 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028795 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Badano JL, Leitch CC, Ansley SJ, May-Simera H, Lawson S, Lewis RA, Beales PL, Dietz HC, Fisher S, Katsanis N (Jan 2006). "Dissection of epistasis in oligogenic Bardet-Biedl syndrome". Nature. 439 (7074): 326–30. Bibcode:2006Natur.439..326B. doi:10.1038/nature04370. PMID   16327777. S2CID   4355521.
6. "Entrez Gene: CCDC28B coiled-coil domain containing 28B".

External links

• Human CCDC28B genome location and CCDC28B gene details page in the UCSC Genome Browser .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.