CISD2

Last updated
CISD2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CISD2 , ERIS, Miner1, NAF-1, WFS2, ZCD2, CDGSH iron sulfur domain 2
External IDs OMIM: 611507; MGI: 1914256; HomoloGene: 36436; GeneCards: CISD2; OMA:CISD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008388

NM_025902

RefSeq (protein)

NP_001008389

NP_080178

Location (UCSC) Chr 4: 102.87 – 102.89 Mb Chr 3: 135.11 – 135.13 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene. [5]

Contents

Function

The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011].

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000145354 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028165 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "CISD2 CDGSH iron sulfur domain 2 [ Homo sapiens (human) ]". National Center for Biotechnology Information . Retrieved 2018-06-04.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.