CWC15

CWC15
Identifiers
Aliases	CWC15 , AD002, C11orf5, Cwf15, HSPC148, ORF5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog
External IDs	MGI: 1913320 HomoloGene: 9499 GeneCards: CWC15
Gene location (Human)
Chr.	Chromosome 11 (human)
End	94,973,586 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	14,421,873 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; vastus lateralis muscle; ; biceps brachii; ; body of tongue; ; Achilles tendon; ; superior surface of tongue; ; deltoid muscle; ; lactiferous duct; ; external globus pallidus; ; pons;
	Top expressed in
	morula; ; yolk sac; ; lip; ; ganglionic eminence; ; supraoptic nucleus; ; mirror; ; cumulus cell; ; spermatocyte; ; thymus; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ; RNA binding ;
Cellular component	catalytic step 2 spliceosome ; spliceosomal complex ; nucleus ; nucleoplasm ; mitochondrion ; nuclear speck ; U2-type catalytic step 2 spliceosome ;
Biological process	mRNA processing ; RNA splicing ; mRNA splicing, via spliceosome ; mRNA cis splicing, via spliceosome ;
	Sources:Amigo / QuickGO
Orthologs
	51503
	66070
	ENSG00000150316
	ENSMUSG00000004096
	Q9P013
	Q9JHS9
	NM_016403 ; NM_001363371 ; NM_001363372
	NM_023153
	NP_057487 ; NP_001350300 ; NP_001350301
	NP_075642
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Protein CWC15 homolog is a protein that in humans is encoded by the CWC15 gene.^[5]^[6]^[7]

Interactions

CWC15 has been shown to interact with CDC5L.^[8]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000150316 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004096 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.
↑ Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould KL (Mar 2002). "Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs". Mol Cell Biol. 22 (7): 2011–24. doi:10.1128/MCB.22.7.2011-2024.2002. PMC 133674 . PMID 11884590.
↑ "Entrez Gene: HSPC148 hypothetical protein HSPC148".
↑ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846 . PMID 11101529.

External links

Human CWC15 genome location and CWC15 gene details page in the UCSC Genome Browser .

Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316 . PMID 15342556.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000150316 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004096 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10873569-5] O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.

[pmid11884590-6] Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould KL (Mar 2002). "Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs". Mol Cell Biol. 22 (7): 2011–24. doi:10.1128/MCB.22.7.2011-2024.2002. PMC 133674 . PMID 11884590.

[entrez-7] "Entrez Gene: HSPC148 hypothetical protein HSPC148".

[pmid11101529-8] Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846 . PMID 11101529.

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CWC15

Contents

Interactions

Related Research Articles

References

External links

Further reading