Calcium-regulated heat stable protein 1

CARHSP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3AQQ
Identifiers
Aliases	CARHSP1 , CRHSP-24, CSDC1, CRHSP24, calcium regulated heat stable protein 1
External IDs	OMIM: 616885; MGI: 1196368; HomoloGene: 8632; GeneCards: CARHSP1; OMA:CARHSP1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p13.2 Start 8,852,942 bp [1] End 8,869,012 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16 A1|16 4.26 cM Start 8,476,444 bp [2] End 8,490,019 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis ganglionic eminence ventricular zone right adrenal gland right adrenal cortex left adrenal gland left adrenal cortex right lobe of liver right lung Top expressed in lens granulocyte cumulus cell epithelium of lens fetal liver hematopoietic progenitor cell secondary oocyte medial ganglionic eminence tibiofemoral joint blood renal corpuscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function mRNA 3'-UTR binding DNA binding phosphatase binding protein binding RNA binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasmic exosome (RNase complex) cytosol P-body P granule cytoplasm Biological process intracellular signal transduction regulation of transcription, DNA-templated regulation of mRNA stability regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23589 52502 Ensembl ENSG00000153048 ENSMUSG00000008393 UniProt Q9Y2V2 Q9CR86 RefSeq (mRNA) NM_001042476 NM_001278260 NM_001278261 NM_001278262 NM_001278263 NM_001278264 NM_001278265 NM_001278266 NM_014316 NM_025821 RefSeq (protein) NP_001035941 NP_001265189 NP_001265190 NP_001265191 NP_001265192 NP_001265193 NP_001265194 NP_001265195 NP_055131 NP_080097 Location (UCSC) Chr 16: 8.85 – 8.87 Mb Chr 16: 8.48 – 8.49 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-regulated heat stable protein 1 (CARHSP1) also known as calcium-regulated heat-stable protein of 24 kDa (CRHSP-24) is a protein that in humans is encoded by the CARHSP1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000153048 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000008393 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Groblewski GE, Yoshida M, Bragado MJ, Ernst SA, Leykam J, Williams JA (September 1998). "Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells". J Biol Chem. 273 (35): 22738–44. doi: 10.1074/jbc.273.35.22738 . PMID   9712905.
6. "Entrez Gene: CARHSP1 calcium regulated heat stable protein 1, 24kDa".

Further reading

• Wishart MJ, Dixon JE (2002). "The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production". Proc. Natl. Acad. Sci. U.S.A. 99 (4): 2112–7. Bibcode:2002PNAS...99.2112W. doi: 10.1073/pnas.251686198 . PMC   122327 . PMID   11842224.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID   12801884.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID   16083285.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.