Carl R. Woese Institute for Genomic Biology

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Carl R. Woese Institute for Genomic Biology
Institute for Genomic Biology, University of Illinois Campus July 2013.jpg
The Carl R. Woese Institute for Genomic Biology, with the Morrow Plots in the foreground
Established2006
MissionTo advance life sciences research and stimulate bioeconomic development.
FocusResearch in systems biology, cellular and metabolic engineering and genome technology.
Director Gene E. Robinson
Address1206 W Gregory Drive
Location
Urbana
,
Illinois
,
United States of America
Website http://www.igb.illinois.edu/

The Carl R. Woese Institute for Genomic Biology (IGB) is an interdisciplinary facility for genomics research at the University of Illinois Urbana-Champaign. The Institute was built in 2006 to centralize biotechnology research at the University of Illinois. Current research at the IGB explores the genomic bases of a wide range of phenomena, including the progression of cancer, the ecological impact of global change, tissue and organ growth, and the diversity of animal behavior. [1]

Contents

History

Construction

Plans for what would become the Carl R. Woese Institute for Genomic Biology (IGB) were formed in the late 1990s.[ citation needed ] In 2000, $67.5 million was appropriated by the state of Illinois for its construction. [2] Due to economic hardships, the state halted plans for construction in 2001. [3] In 2002, funds were re-appropriated. [4] Construction began in April 2004 and was completed in November 2006. The building was dedicated in March 2007.[ citation needed ] Initially named the Institute for Genomic Biology, it officially changed its name to the Carl R. Woese Institute for Genomic Biology in 2015 to honor the scientific contributions of Carl R. Woese.[ citation needed ]

Leadership

The IGB was initially led by Harris Lewin, then a professor in the Department of Animal Sciences at the University of Illinois. Lewin served as the founding director until 2011, when he accepted the position of Research Vice Chancellor at University of California, Davis. Gene E. Robinson, a professor in the Entomology department, took over as Interim Director, and was named the new Director of IGB in January 2012. [5]

Research

The IGB houses approximately 130 faculty and 600 graduate students, postdoctoral fellows, and research personnel. Research is organized into themes, they are reviewed every five years; new themes may be added or existing themes modified to reflect the current state of genomics research. Current themes are listed below: [6]

Research themes and Initiatives at the Carl R. Woese Institute for Genomic Biology
ThemeTheme LeaderDescription of Research
Anticancer Discovery from Pets to People (ACPP) Paul Hergenrother Develops cancer treatments in pet animals that translate to human disease.
Biosystems Design (BSD) Huimin Zhao Engineers microorganisms and plants to address challenges in health and sustainability.
Center for Advanced Biofuels and Bioproducts Innovation (CABBI)Andrew LeakeyDevelop ways to grow bioenergy crops, transform biomass into valuable chemicals, and market the resulting bioproducts.
Center for Artificial Intelligence and Modeling (CAIM)Sergei Maslow and Olgica MilenkovicStudies complicated scientific processes using modeling and machine learning.
Center for Genomic Diagnostics (CGD) Brian Cunningham Employs new technologies to diagnose and treat diseases at a lower cost.
Center for Indigenous Science (CIS)Ripan Malhi and Jenny Davis Uses Indigenous Science frameworks to promote research that is ethical, sustainable, and community-focused.
Environmental Impact on Reproductive Health (EIRH)Indrani Bagchi and Jodi FlawsFocuses on the effects of environment, diet, and stress on reproductive health.
Gene Networks in Neural and Developmental Biology (GNDP)Alison BellExamines the effects of coordinated gene activity on biological diversity.
Genomic Ecology of Global Change (GEGC) Donald Ort Studies the intersection of plant genomics and global climate change.
Genomic Security and Privacy (GSP)Carl GunterUses new technologies to protect the privacy and security of genomic information.
Infection Genomics for One Health (IGOH) Rachel Whitaker Examines how microbes in human-inhabited environments influence health and disease.
Microbiome Metabolic Engineering (MME)Michael Miller and Carin VanderpoolExplores the relationships among human microbiota, environment, and health.
Mining for anti-infectious Molecules from Genomes (MMG) Wilfred van der Donk Discovers small molecules that might provide new medical solutions.
Scott H. Fisher Multi-Cellular Engineered Living Systems (M-CELS)Hyunjoon KongCreates machines made of living cells.
Regenerative Biology and Tissue Engineering (RBTE)Brendan HarleyStudies the replacement or regeneration of tissues and organs.

Notable awards and partnerships

In 2007, the University of Illinois, along with the University of California, formed a partnership with the energy company BP as part of a major research project to develop bioenergy sources. The University of Illinois facility is based in the IGB. [7]

In 2011, Abbott Nutrition and the University of Illinois collaborated to establish a research center for the study of the relationship between nutrition and cognition, entitled the Center for Nutrition, Learning, and Memory (CNLM). Several campus units are currently partners of CNLM, including the IGB. [8]

Building

The IGB is located on the south side of the University of Illinois main campus at Urbana-Champaign. The building was constructed by the architecture firm CUH2A (now a part of the architecture-engineering company HDR). The exterior of the building was designed to include elements of Georgian architecture. [9] Inside, each Research Theme has a large, open plan laboratory space and additional work rooms and office and meeting area. [1] The building stands adjacent to the Morrow Plots.

See also

Notes

    Related Research Articles

    <span class="mw-page-title-main">Carl Woese</span> American microbiologist (1928–2012)

    Carl Woese was an American microbiologist and biophysicist. Woese is famous for defining the Archaea in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal RNA, a technique that has revolutionized microbiology. He also originated the RNA world hypothesis in 1967, although not by that name. Woese held the Stanley O. Ikenberry Chair and was professor of microbiology at the University of Illinois Urbana–Champaign.

    <span class="mw-page-title-main">Beckman Institute for Advanced Science and Technology</span>

    The Beckman Institute for Advanced Science and Technology is a unit of the University of Illinois Urbana-Champaign dedicated to interdisciplinary research. A gift from scientist, businessman, and philanthropist Arnold O. Beckman (1900–2004) and his wife Mabel (1900–1989) led to the building of the Institute which opened in 1989. It is one of five institutions which receive support from the Arnold and Mabel Beckman Foundation on an ongoing basis. Current research at Beckman involves the areas of molecular engineering, intelligent systems, and imaging science. Researchers in these areas work across traditional academic boundaries in scientific projects that can lead to the development of real-world applications in medicine, industry, electronics, and human health across the lifespan.

    <span class="mw-page-title-main">University of Illinois College of Liberal Arts and Sciences</span> College in Illinois, U.S.

    The College of Liberal Arts and Sciences (LAS) is the largest college of the University of Illinois Urbana-Champaign. The college was established in 1913 through the merger of the College of Literature and Arts and the College of Science. The college offers seventy undergraduate majors, as well as master's and Ph.D. programs. As of 2020, there are nearly 12,000 undergraduate students and 2,500 graduate students attending the College of Liberal Arts and Sciences.

    <span class="mw-page-title-main">Morrow Plots</span> United States historic place

    The Morrow Plots is an experimental agricultural field at the University of Illinois Urbana-Champaign. Named for Professor George E. Morrow, it is the oldest such field in the United States and the second oldest in the world. It was established in 1876 as the first experimental corn field at an American college and continues to be used today, although with three half-acre plots, instead of the original ten. The site was designated a National Historic Landmark on May 23, 1968. The fields are managed by the College of Agricultural, Consumer, and Environmental Sciences.

    Richard H. Herman is a mathematician, currently Professor Emeritus of Mathematics, who had served as the Chancellor of the University of Illinois at Urbana-Champaign from 2005-2009. He previously served there as Provost and Vice Chancellor of Academic Affairs since 1998. As provost he garnered support for, and administered, a “faculty excellence” program designed to bring established faculty to the institution. Throughout his administrative tenure, sponsored research at the university increased by more than 50%.

    Huimin Zhao is the Steven L. Miller Chair Professor of Chemical and Biomolecular Engineering at the University of Illinois, Urbana-Champaign, as well as the leader of the Biosystems Design research theme in the Carl R. Woese Institute for Genomic Biology. His research focuses on directed evolution, metabolic engineering, bioinformatics and high throughput technologies.

    Gene Ezia Robinson is an American entomologist, Director of the Carl R. Woese Institute for Genomic Biology and National Academy of Sciences member. He pioneered the application of genomics to the study of social behavior and led the effort to sequence the honey bee genome. On February 10, 2009, his research was famously featured in an episode of The Colbert Report whose eponymous host referred to the honey Dr. Robinson sent him as "pharmaceutical-grade hive jive".

    IGB may refer to:

    Ravishankar K. Iyer is the George and Ann Fisher Distinguished Professor of Engineering at the University of Illinois at Urbana-Champaign. He is a specialist in reliable and secure networks and systems.

    <span class="mw-page-title-main">Lawrence B. Schook</span>

    Lawrence B. Schook was the vice president for research at the University of Illinois. He oversaw the $1 billion research portfolio across all three campuses. A scholar in comparative genomics and the exploitation of genomic diversity to understand traits and disease, Dr. Schook focuses his research on genetic resistance to disease, regenerative medicine, and using genomics to create animal models for biomedical research. He led the international pig genome-sequencing project, which produced a draft of the pig genome allowing researchers to offer insights into diseases that afflict pigs and humans.

    Harris A. Lewin, an American biologist, is a professor of evolution and ecology and Robert and Rosabel Osborne Endowed Chair at the University of California, Davis. He is a member of the National Academy of Sciences. In 2011, Lewin won the Wolf Prize in Agriculture for his research into cattle genomics. Lewin chairs the working group for the Earth BioGenome Project, a moonshot for biology that aims to sequence, catalog, and characterize the genomes of all of Earth’s eukaryotic biodiversity over a period of 10 years. Lewin is a founding co-editor of the Annual Review of Animal Biosciences, first published in 2013.

    Nigel David Goldenfeld is a Professor of Physics at the University of California, San Diego. Preivously he worked at the University of Illinois at Urbana-Champaign, where he served as director of the NASA Astrobiology Institute for Universal Biology, and the leader of the Biocomplexity group at Carl R. Woese Institute for Genomic Biology.

    Neal J. Cohen is a professor of psychology in the Cognitive Neuroscience division of the University of Illinois at Urbana–Champaign. He is appointed as a full-time faculty member in the Beckman Institute for Advanced Science and Technology at the University of Illinois. He is the founding director of the Center for Nutrition, Learning, and Memory (CNLM), a partnership of the University of Illinois and Abbott Laboratories as of 2011. He is also the founding director of the Interdisciplinary Health Sciences Initiative (IHSI) at the University of Illinois, formed 2014.

    Douglas A. Mitchell is a Professor of Chemistry at the University of Illinois at Urbana-Champaign. He holds an affiliate appointment in the Department of Microbiology and is a faculty member of the Carl R. Woese Institute for Genomic Biology. His research focuses on the chemical biology of natural products. He is known mainly for his work on the biosynthetic enzymology of ribosomally synthesized and post-translationally modified peptides (RiPPs) and genome-guided natural product discovery.

    <span class="mw-page-title-main">Stephen P. Long</span> British plant physiologist

    Stephen Patrick Long is a British-born American environmental plant physiologist and member of the National Academy of Sciences studying how to improve photosynthesis to increase the yield of food and biofuel crops. He is the Stanley O. Ikenberry Chair Professor of Plant Biology and Crop Sciences at the University of Illinois and visiting professor in Plant Sciences at Lancaster University and at Oxford University, UK. His work, published in Science, proved that photosynthesis can be manipulated to increase plant productivity—an idea once considered the holy grail of plant biology. Long has added to our understanding of the long-term impacts of climate change, such as rising levels of carbon dioxide and ozone on plants. He has briefed former President George W. Bush and the Vatican, as well as Bill Gates and Anne, Princess Royal, on food security and bioenergy.

    Jonathan V Sweedler is an American chemist specializing in bioanalytical chemistry, neurochemistry and cell to cell biology and behavior. He is the James R. Eiszner Family Endowed Chair in Chemistry at the University of Illinois at Urbana-Champaign. Additionally, he holds a faculty appointment in the Beckman Institute. He is also an Elected Fellow to the American Chemical Society, for which he is also the society's Editor in Chief for the journal Analytical Chemistry.

    <span class="mw-page-title-main">Jian Ma (computer scientist)</span> American computer scientist

    Jian Ma is an American computer scientist and computational biologist. He is the Ray and Stephanie Lane Professor of Computational Biology in the School of Computer Science at Carnegie Mellon University. He is a faculty member in the Ray and Stephanie Lane Computational Biology Department. His lab develops machine learning algorithms to study the structure and function of the human genome and cellular organization and their implications for health and disease. During his Ph.D. and postdoc training, he developed algorithms to reconstruct the ancestral mammalian genome. His research group has recently pioneered a series of new machine learning methods for 3D epigenomics, comparative genomics, spatial genomics, and single-cell analysis. He received an NSF CAREER award in 2011. In 2020, he was awarded a Guggenheim Fellowship in Computer Science. He is an elected Fellow of the American Association for the Advancement of Science. He leads an NIH 4D Nucleome Center to develop machine learning algorithms to better understand the cell nucleus. He is the Program Chair for RECOMB 2024.

    <span class="mw-page-title-main">Lisa Ainsworth</span> American molecular biologist

    Elizabeth Anna Ainsworth is an American plant physiologist currently employed by the United States Department of Agriculture (USDA) Agricultural Research Service (ARS). She also is an adjunct professor of the University of Illinois at Urbana-Champaign (UIUC), a Fellow of the American Association for the Advancement of Science (AAAS) and was awarded the 2018 Crop Science Society of America Presidential Award. She is known for her work concerning the effects of specific atmospheric pollutants, including ozone and carbon dioxide, on the productivity of selected major crops such as corn and soybeans.

    <span class="mw-page-title-main">Donald R. Ort</span> American botanist and biochemist

    Donald Richard Ort is an American botanist and biochemist. He is the Robert Emerson Professor of Plant Biology and Crop Sciences at the University of Illinois at Urbana-Champaign where he works on improving crop productivity and resilience to climate change by redesigning photosynthesis. He is a member of the National Academy of Sciences (NAS) and a fellow of the American Association for the Advancement of Science (AAAS) and American Society of Plant Biologists (ASPB).

    References

    1. 1 2 "The Institute for Genomic Biology: Where science meets society" . Retrieved 2013-06-10.
    2. "Governor expected to unveil $1 billion technology initiative". Associated Press Services. 2000-01-29.
    3. McDermott, Kevin (2001-11-28). "Ryan pares $219 million from Illinois budget". St. Louis Post-Dispatch.
    4. "State gives U. of I. $123 million for tech buildings". Midwest Construction. December 2002.
    5. ""Curriculum Vita of Gene Robinson"" . Retrieved August 8, 2024.
    6. "Our Research | Carl R. Woese Institute for Genomic Biology". www.igb.illinois.edu. Retrieved 2021-11-14.
    7. Mercer, David (2007-02-01). "Two U.S. universities chosen by BP for partnership in alternative-fuels research". Associated Press Worldstream.
    8. des Garennes, Christine (2011-12-22). "University of Illinois, Abbott developing nutrition, cognition research center". The News-Gazette.
    9. "Award winning Institute for Genomic Biology designed by CUH2A opens at the University of Illinois Urbana-Champaign". Business Wire. 2007-04-18.

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