Cathy Price | |
---|---|
Born | Catherine J. Price |
Alma mater | Birkbeck College |
Scientific career | |
Fields | Cognitive neuroscience |
Institutions | University College London |
Thesis | (1990) |
Academic advisors | Karl Friston |
Notable students | Maria Luisa Gorno-Tempini |
Website | www |
Catherine "Cathy" J. Price FRS FMedSci is a Professor of Cognitive Neuroscience and Director of the Wellcome Trust Centre for Neuroimaging at University College London. [1]
Her overarching research goal is to provide a model of the neural basis of language [2] that predicts and explains speech and language difficulties and their recovery after brain damage (stroke or neurosurgery). [3] She is a world-leading, renowned neuroscientist. [4]
Price is also Director of the Wellcome Centre for Human Neuroimaging. [5]
Price obtained her bachelor's degree in 1984, and her PhD in 1990, both from Birkbeck College. [6]
Professor Kia Nobre, who nominated Price for the 5th Suffrage award for Life Sciences, said: "She blossomed through the trenches of a very macho world with gentle words, generous deeds, scientific commitment and rigour, genuine translation of research to clinical benefit, and humour." [7]
Price originally trained as a neuropsychologist studying reading and object recognition in patients with brain damage. In 1991, she joined the Medical Research Council (MRC) cyclotron unit at the inception of human brain mapping and used PET scanning to provide new insights into the functional anatomy of reading, speech perception, speech production and semantics.
In 1995, Price moved to University College London using MRI scanning to show how language abilities and IQ are reflected in brain structure. For example, by combining structural and functional imaging data from healthy participants, Price has shown the remarkable effect that learning has on the structure of the brain. This is illustrated in a series of 3 Nature papers that map structural brain changes associated with (i) learning a second language, [8] (ii) learning to read in adulthood [9] and (iii) naturally occurring changes in verbal and nonverbal IQ in the teenage brain. [10]
Price has made two strong theoretical claims. Contrary to traditional views, her “cognitive ontologies” theory [11] claimed that there are no parts of the human brain that are dedicated to language processing. Instead, specialisation for all types of language processing emerge through cross-talk among unique combinations of areas that are each involved in many other non-linguistic functions. Redefining the functional components of language, in terms of the underlying neural systems would, Price proposes, allow us to generate cognitive models that are both physiologically plausible and clinically useful. [12] Her “cognitive degeneracy” theory [13] claimed that the same language task can be supported by different neural pathways, and that an understanding of when and why different neural pathways are used is essential for understanding how patients recover language after brain damage.
Since 2012, Price has turned her attention to developing a tool for predicting language outcome and recovery after stroke (the PLORAS study). [14] To this end, she is creating a database that provides easy access to multiple sources of information (behaviour, demographics, brain structure and function) from thousands of stroke survivors. Predictions for new patients are based on how others with similar brain damage and demographics were observed to recover from the same symptoms. The same data, and the theory of cognitive degeneracy, can also be used to explain recovery in terms of the degree to which patients have preserved the set of neural pathways needed to produce speech and language (Seghier and Price, 2018). [15]
In March 2020, her h-index is 86 from a total of 322 papers, with more than 24,000 citations. [16]
Cognitive neuroscience is the scientific field that is concerned with the study of the biological processes and aspects that underlie cognition, with a specific focus on the neural connections in the brain which are involved in mental processes. It addresses the questions of how cognitive activities are affected or controlled by neural circuits in the brain. Cognitive neuroscience is a branch of both neuroscience and psychology, overlapping with disciplines such as behavioral neuroscience, cognitive psychology, physiological psychology and affective neuroscience. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neurobiology, and computational modeling.
Cognitive neuropsychology is a branch of cognitive psychology that aims to understand how the structure and function of the brain relates to specific psychological processes. Cognitive psychology is the science that looks at how mental processes are responsible for our cognitive abilities to store and produce new memories, produce language, recognize people and objects, as well as our ability to reason and problem solve. Cognitive neuropsychology places a particular emphasis on studying the cognitive effects of brain injury or neurological illness with a view to inferring models of normal cognitive functioning. Evidence is based on case studies of individual brain damaged patients who show deficits in brain areas and from patients who exhibit double dissociations. Double dissociations involve two patients and two tasks. One patient is impaired at one task but normal on the other, while the other patient is normal on the first task and impaired on the other. For example, patient A would be poor at reading printed words while still being normal at understanding spoken words, while the patient B would be normal at understanding written words and be poor at understanding spoken words. Scientists can interpret this information to explain how there is a single cognitive module for word comprehension. From studies like these, researchers infer that different areas of the brain are highly specialised. Cognitive neuropsychology can be distinguished from cognitive neuroscience, which is also interested in brain damaged patients, but is particularly focused on uncovering the neural mechanisms underlying cognitive processes.
Functional neuroimaging is the use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. It is primarily used as a research tool in cognitive neuroscience, cognitive psychology, neuropsychology, and social neuroscience.
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Christopher Donald Frith, is a psychologist and professor emeritus at the Wellcome Trust Centre for Neuroimaging at University College London. Visiting Professor at the Interacting Minds Centre at Aarhus University, Research Fellow at the Institute of Philosophy and Quondam Fellow of All Souls College, Oxford.
In neuropsychology, dissociation involves identifying the neural substrate of a particular brain function through identification of case studies, neuroimaging, or neuropsychological testing.
The Wellcome Centre for Human Neuroimaging, formerly the Wellcome Trust Centre for Neuroimaging at University College London is an interdisciplinary centre for neuroimaging research based in London, United Kingdom.
Jonathon Stevens "Jon Driver" was a psychologist and neuroscientist. He was a leading figure in the study of perception, selective attention and multisensory integration in the normal and damaged human brain.
Neurorehabilitation is a complex medical process which aims to aid recovery from a nervous system injury, and to minimize and/or compensate for any functional alterations resulting from it.
Various aspects of multilingualism have been studied in the field of neurology. These include the representation of different language systems in the brain, the effects of multilingualism on the brain's structural plasticity, aphasia in multilingual individuals, and bimodal bilinguals. Neurological studies of multilingualism are carried out with functional neuroimaging, electrophysiology, and through observation of people who have suffered brain damage.
The UCL Queen Square Institute of Neurology is an institute within the Faculty of Brain Sciences of University College London (UCL) and is located in London, United Kingdom. Together with the National Hospital for Neurology and Neurosurgery, an adjacent facility with which it cooperates closely, the institute forms a major centre for teaching, training and research in neurology and allied clinical and basic neurosciences.
Eleanor Anne Maguire is an Irish neuroscientist. Since 2007, she has been Professor of Cognitive Neuroscience at University College London where she is also a Wellcome Trust Principal Research Fellow.
The following outline is provided as an overview of and topical guide to brain mapping:
Sophie Kerttu Scott is a British neuroscientist and Wellcome Trust Senior Fellow at University College London (UCL). Her research investigates the cognitive neuroscience of voices, speech and laughter particularly speech perception, speech production, vocal emotions and human communication. She also serves as director of UCL's Institute of Cognitive Neuroscience.
Social cognitive neuroscience is the scientific study of the biological processes underpinning social cognition. Specifically, it uses the tools of neuroscience to study "the mental mechanisms that create, frame, regulate, and respond to our experience of the social world". Social cognitive neuroscience uses the epistemological foundations of cognitive neuroscience, and is closely related to social neuroscience. Social cognitive neuroscience employs human neuroimaging, typically using functional magnetic resonance imaging (fMRI). Human brain stimulation techniques such as transcranial magnetic stimulation and transcranial direct-current stimulation are also used. In nonhuman animals, direct electrophysiological recordings and electrical stimulation of single cells and neuronal populations are utilized for investigating lower-level social cognitive processes.
Rex Eugene Jung is an American psychologist who has researched on the neural basis of human intelligence and creativity. He is an assistant professor at the University of New Mexico, where he is the director of neuropsychological services. Jung is also a practicing psychologist at his private clinic.
Kathryn Emma Watkins is an experimental psychologist in the Wellcome Trust centre for integrative neuroimaging at the University of Oxford and a tutorial fellow at St Anne's College, Oxford. Her research investigates the brain processes that underlie speech, language and development.
Steven L. Small is the Aage and Margareta Møller Distinguished Professor in Behavioral and Brain Sciences at the University of Texas at Dallas, and dean of its School of Behavioral and Brain Sciences. Small is a specialist in the neurobiology of language.
Heidi Johansen-Berg is a Professor of Cognitive Neuroscience and Director of the Wellcome Centre for Integrative Neuroimaging at the University of Oxford. She studies brain plasticity in the context of stroke rehabilitation and aging.