Cdc42 binding protein kinase beta

Last updated
CDC42BPB
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CDC42BPB , MRCKB, CDC42 binding protein kinase beta
External IDs OMIM: 614062 MGI: 2136459 HomoloGene: 55945 GeneCards: CDC42BPB
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006035

NM_183016

RefSeq (protein)

NP_006026
NP_006026.3

NP_898837

Location (UCSC) Chr 14: 102.93 – 103.06 Mb Chr 12: 111.29 – 111.38 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

CDC42 binding protein kinase beta is a protein that in humans is encoded by the CDC42BPB gene. [5]

Contents

Function

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rats suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000198752 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021279 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: CDC42 binding protein kinase beta" . Retrieved 2017-05-31.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.