Centre for DNA Fingerprinting and Diagnostics

Last updated

Centre for DNA Fingerprinting & Diagnostics
CDFD Uppal Campus.jpg
TypeAutonomous
Established1996
Director K Thangaraj
Location
Hyderabad
,
Telangana
,
India
Campus Urban - Uppal
Website cdfd.org.in

Centre for DNA Fingerprinting and Diagnostics (CDFD) is an Indian biotechnology research centre, located in Hyderabad, India, operated by the Department of Biotechnology, Ministry of Science and Technology, Government of India. CDFD is a Sun Microsystems centre of excellence in medical bio-informatics, supported with a strong bioinformatics facility, and is the India node of the EMBnet. [1] In addition, DNA fingerprinting and diagnostics services provided by the centre support some of the activities. [2] [3] [4] The centre utilises the Combined DNA Index System for DNA profile matching. The CDFD and the U.S. Federal Bureau of Investigation signed a memorandum of understanding in 2014 for the acquisition of CODIS. [5]

Contents

CDFD receives funding from other agencies like the Wellcome Trust on specific collaborative projects. [6] The centre is recognised by the University of Hyderabad and Manipal University for pursuing a doctor of philosophy in life sciences. [7] Research at CDFD has focused largely on molecular epidemiology of bacterial pathogens, structural genetics, molecular genetics, bioinformatics and computational biology. [8]

History

Centre for DNA Fingerprinting and Diagnostics (CDFD), Uppal campus CDFD campus.jpg
Centre for DNA Fingerprinting and Diagnostics (CDFD), Uppal campus

CDFD was conceptualised by then CCMB director Lalji Singh. It evolved into its current form of a modern institution encompassing both basic and applied research in diverse areas of modern biology under its founder director, Seyed E. Hasnain (former vice-chancellor of the University of Hyderabad), who pursued this aim aggressively during his tenure from 1999 to 2005. The centre is equipped with instrumentation and computing infrastructure to facilitate working in frontier areas of research in life sciences. There are twenty-two groups working on diverse research areas and the centre continues to attract leaders in related disciplines. [9]

Campus

CDFD started its operations at the Centre for Cellular and Molecular Biology, a Council of Scientific and Industrial Research organisation, and was housed in an interim building in Nacharam from early 1999 to December 2008. [10] In 2009, it was moved to a sprawling new building in Gandipet locality at the outskirts of Hyderabad. But, due to some of the governmental objections pertaining to the proximity of the new campus to Osman Sagar lake, any of the wet-lab work was not allowed. As a result, the building raised at Gandipet was completely vacated by CDFD in early 2009 [11] and institute operated from its rented building in Nampally and with an MoU for the diagnostic screening with the Nizam's Institute of Medical Sciences (NIMS).

Following the appointment of Dr. Debashis Mitra as its new director w.e.f. 1 November 2017, CDFD commenced its move to its permanent campus in Uppal, and as of 15 March 2018 the institute is housed in its permanent building next to Nagole Metro Station.

See also

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Lalji Singh FNA, FASc was an Indian scientist who worked in the field of DNA fingerprinting technology in India, where he was popularly known as the "Father of Indian DNA fingerprinting". Singh also worked in the areas of molecular basis of sex determination, wildlife conservation forensics and evolution and migration of humans. In 2004, he received the Padma Shri in recognition of his contribution to Indian science and technology.

Ranjan Sen is an Indian microbiologist, biophysicist and a senior scientist as well as the head of the Laboratory of Transcription at the Centre for DNA Fingerprinting and Diagnostics. Known for his studies in the field of prokaryotic transcription, Sen is an elected fellow of the Indian National Science Academy and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2007.

Sangita Mukhopadhyay is an Indian molecular cell biologist, immunologist and the head of the molecular biology group at the Centre for DNA Fingerprinting and Diagnostics. Known for her studies on immunosuppression and infection biology, Mukhopadhyay is an elected fellow of all the three major Indian science academies namely the Indian National Science Academy, the Indian Academy of Sciences and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2008.

Sunil Kumar Manna is an Indian immunologist and the head of the immunology lab of the Centre for DNA Fingerprinting and Diagnostics. He is known for his studies on cell signaling and apoptosis. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2009.

Ganesh Nagaraju is an Indian biochemist, geneticist, cancer biologist and a full professor at the Department of Biochemistry of the Indian Institute of Science. He has been studying DNA damage responses in mammalian cells, and mechanisms underlying chromosome instability genetic diseases and cancer. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, for his contributions to biosciences, in 2015. In 2018, Nagaraju received the Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Sciences from CSIR. This award is given in recognition of outstanding contributions to Science and Technology, and is considered one of the highest awards for science in India.

Subhadeep Chatterjee is an Indian molecular biologist and a scientist at the Centre for DNA Fingerprinting and Diagnostics (CDFD). A member of Guha Research Conference, he is known for his studies on plant-microbe interactions and heads the Lab of Plant-Microbe Interactions at CDFD where he hosts several researchers.

Maddika Subba Reddy is an Indian cell biologist and the head of the Laboratory of Cell Death and Cell Survival (LCDCS) of the Centre for DNA Fingerprinting and Diagnostics. A Wellcome-DBT Senior Fellow, Reddy is known for his studies cell signaling and phosphatases. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.

References

  1. ↑ "The Hindu : Decks cleared for Sun Micro centre at CDFD". Hinduonnet.com. 12 February 2004. Archived from the original on 25 January 2013. Retrieved 21 August 2012.{{cite news}}: CS1 maint: unfit URL (link)
  2. ↑ "CDFD helps identify U'khand copter crash victims". The Times of India . 2 July 2013. Archived from the original on 3 July 2013.
  3. ↑ "States / Andhra Pradesh : CDFD gets samples of Tiwari, two others". The Hindu. Chennai, India. 2 June 2012. Archived from the original on 3 June 2012. Retrieved 21 August 2012.
  4. ↑ "Air crash: CDFD to conduct DNA tests". The Hindu . Chennai, India. 24 May 2010. Archived from the original on 30 May 2010.
  5. ↑ "CDFD to Use FBI's CODIS Software for DNA Profile Matching".
  6. ↑ "DBT alliance" . Retrieved 21 August 2012.[ permanent dead link ]
  7. ↑ "Academics" (PDF). Retrieved 21 August 2012.
  8. ↑ Bashyam MD, Chaudhary AK, Manjari S, Nagarajaram HA, Devi AR, Bashyam L, Reddy EC, Dalal A. Molecular genetic analysis of MSUD from India reveals mutations causing altered protein truncation affecting the C-termini of E1α and E1β. J Cell Biochem. 2012 May 16.
  9. ↑ "Best Diagnostic Centre in Lucknow". www.ipsumcare.com/. 21 November 2002. Archived from the original on 17 July 2011. Retrieved 21 August 2012.
  10. ↑ "Andhra Pradesh / Hyderabad News : CDFD may be shifted to IISM premises". The Hindu . Chennai, India. 4 September 2010. Archived from the original on 8 November 2012. Retrieved 21 August 2012.
  11. ↑ TNN (18 June 2011). "CDFD campus to come up at Survey of India premises". The Times of India . Archived from the original on 19 April 2012. Retrieved 21 August 2012.
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