Chlorozotocin

Last updated

Chlorozotocin
Chlorozotocin (Haworth).svg
Clinical data
ATC code
  • none
Identifiers
  • 2-{[(2-Chloroethyl)(nitroso)carbamoyl]amino}-2-deoxy-D-glucose
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C9H16ClN3O7
Molar mass 313.69 g·mol−1
3D model (JSmol)
  • ClCCN(N=O)C(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO
  • InChI=1S/C9H16ClN3O7/c10-1-2-13(12-20)9(19)11-5(3-14)7(17)8(18)6(16)4-15/h3,5-8,15-18H,1-2,4H2,(H,11,19)/t5-,6+,7+,8+/m0/s1 X mark.svgN
  • Key:MKQWTWSXVILIKJ-LXGUWJNJSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Chlorozotocin is a nitrosourea. It is used for cancer therapy.[ citation needed ]

The International Agency for Research on Cancer concluded it was "probably carcinogenic" in 1990 [1]

It is an analogue of streptozotocin. [2]

References

  1. ↑ Humans, IARC Working Group on the Evaluation of Carcinogenic Risk to (1990). SUMMARY OF FINAL EVALUATIONS. International Agency for Research on Cancer.
  2. ↑ Wolfe MM (2006). Therapy of digestive disorders. Elsevier Health Sciences. p. 477. ISBN   978-1-4160-0317-5.


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