Christopher Barner-Kowollik

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Christopher Barner-Kowollik
Personal details
Born1973 (age 5051)
West Germany
Occupation Materials scientist

Christopher Barner-Kowollik (born 1973) is a German-Australian materials scientist who is an Australian Research Council Laureate Fellow working in macromolecular photochemistry. [1] He is currently Senior Deputy Vice-Chancellor and vice-president (Research) of the Queensland University of Technology (QUT) and Distinguished Professor within the School of Chemistry and Physics at the QUT in Brisbane. From 2017 to 2024 he was editor-in-chief of the Royal Society of Chemistry (RSC) journal Polymer Chemistry , [2] and is an editor for the RSC's journal Chemical Science . [3]  He is a principal investigator within the Soft Matter Materials Laboratory at QUT [4] and associate research group leader at the Karlsruhe Institute of Technology. [5]

Contents

Education and career

After his undergraduate studies of chemistry at the Universities of Constance and Goettingen (Germany), Christopher Barner-Kowollik earned his PhD in physical chemistry (Dr. rer. nat.) from the University of Goettingen in 1999. [6] Following postdoctoral research with Tom Davis at the University of New South Wales, he held academic positions at the Centre for Advanced Macromolecular Design (CAMD), and was appointed Full Professor of Polymer Chemistry in 2006 at the same institution. [7] In 2008, he moved back to Germany, where he became the Chair of Macromolecular Chemistry at the Karlsruhe Institute of Technology (KIT). There he was the founding director of the Collaborative Research Centre SFB 1176 'Molecular Structuring of Soft Matter' established by the German Research Council (DFG). [8] He is a founding PI and thrust speaker in the DFG Excellence Cluster 3D Matter Made to Order. [9]

Barner-Kowollik relocated in 2017 to the Queensland University of Technology (QUT), where he was awarded an Australian Laureate Fellowship and appointed Director of QUT's Soft Matter Materials Laboratory. He is an associate group leader at the KIT's Institute of Nanotechnology and the Institute of Polymer Chemistry and Chemical Technology, after heading a full research group at the KIT until 2020. [10] In December 2019, Barner-Kowollik was appointed Deputy Vice-Chancellor Research and vice-president of QUT [11] and in September 2022 Senior Deputy Vice Chancellor and vice-president (Research). [12]

Research

Barner-Kowollik's research was initially in the field of polymer chemistry and polymer reaction kinetics. [13] [14] Over the course of his career, his research has fused polymer chemistry with organic and photochemistry. These research areas include the development of wavelength-orthogonal, -synergistic, -cooperative and -antagonistic reactions, [15] [16] and their photophysical understanding. [17] [18] His research established the field of highly wavelength-resolved photochemical action plots for photochemical covalent bond formation and cleavage. The development of photochemical action plots demonstrated that molecular absorptivity and photochemical reactivity are oftentimes disparate, [19] [20] which has significant implications for the photochemical synthesis of highly defined macromolecular architectures. [21] [22] The developed photochemical platforms – including out-of-equilibrium light stabilized dynamic materials (LSDMs) [23] - find application for the design of 2D [24] and 3D photolithographic processes [25] [26] [27] as well as in biosystems including single cell scaffolds. [28] Examples of precision photochemistry from his laboratory range from synergistically operating covalent bond forming systems and photoresins [29] requiring two colours of light to cure and examples of pathway independent wavelength orthogonal reaction systems [30] to using different colours of light to selectively adapt soft matter material properties. [31] Christopher Barner-Kowollik has published over 780 peer-reviewed research papers, which have been cited close to 49,000 times. [32]

Awards and recognition

Elected fellowships

Related Research Articles

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<span class="mw-page-title-main">Photochemistry</span> Sub-discipline of chemistry

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<span class="mw-page-title-main">Host–guest chemistry</span> Supramolecular structures held together other than by covalent bonds

In supramolecular chemistry, host–guest chemistry describes complexes that are composed of two or more molecules or ions that are held together in unique structural relationships by forces other than those of full covalent bonds. Host–guest chemistry encompasses the idea of molecular recognition and interactions through non-covalent bonding. Non-covalent bonding is critical in maintaining the 3D structure of large molecules, such as proteins and is involved in many biological processes in which large molecules bind specifically but transiently to one another.

The Passerini reaction is a chemical reaction involving an isocyanide, an aldehyde, and a carboxylic acid to form a α-acyloxy amide. This addition reaction is one of the oldest isocyanide-based multicomponent reactions and was first described in 1921 by Mario Passerini in Florence, Italy. It is typically carried out in aprotic solvents but can also be performed in ionic liquids such as water or deep eutectic solvents. It is a third order reaction; first order in each of the reactants. The Passerini reaction is often used in combinatorial and medicinal chemistry with recent utility in green chemistry and polymer chemistry. As isocyanides exhibit high functional group tolerance, chemoselectivity, regioselectivity, and stereoselectivity, the Passerini reaction has a wide range of synthetic applications.

Click chemistry is an approach to chemical synthesis that emphasizes efficiency, simplicity, selectivity, and modularity in chemical processes used to join molecular building blocks. It includes both the development and use of "click reactions", a set of simple, biocompatible chemical reactions that meet specific criteria like high yield, fast reaction rates, and minimal byproducts. It was first fully described by K. Barry Sharpless, Hartmuth C. Kolb, and M. G. Finn of The Scripps Research Institute in 2001. In this seminal paper, Sharpless argued that synthetic chemistry could emulate the way nature constructs complex molecules, using efficient reactions to join together simple, non-toxic building blocks.

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<span class="mw-page-title-main">Takuzo Aida</span> Japanese polymer chemist

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<span class="mw-page-title-main">Stefan Hecht</span> German chemist (born 1974)

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<span class="mw-page-title-main">Vincenzo Balzani</span> Italian chemist

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Fritz Weigert was a German physical chemist. Weigert has made major contributions in the field of photochemistry. He was born in Berlin. He was the nephew of both Karl Weigert and Paul Ehrlich. He was married to Margarete Behmer. Around 1908, he began teaching and conducting research at Berlin University - after studying there. He was a photochemistry professor at Leipzig University from 1914 until being, like other Jewish scientists, forced out by the Nazis in 1934. On January 1, 1935, he immigrated to England and in 1936 was director of the Physiochemical Department of the Cancer Research Institute at Mount Vernon Hospital, Northwood.

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<span class="mw-page-title-main">Jayaraman Sivaguru</span>

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References

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  17. Kislyak, Anastasia; Kodura, Daniel; Frisch, Hendrik; Feist, Florian; Van Steenberge, Paul H.M.; Barner-Kowollik, Christopher; d'Hooge, Dagmar R. (15 December 2020). "A holistic approach for anthracene photochemistry kinetics". Chemical Engineering Journal. 402: 126259. doi:10.1016/j.cej.2020.126259. ISSN   1385-8947. S2CID   225028511.
  18. Kislyak, Anastasia; Frisch, Hendrik; Gernhardt, Marvin; Steenberge, Paul H. M. Van; D'hooge, Dagmar R.; Barner-Kowollik, Christopher (2020). "Time-Dependent Differential and Integral Quantum Yields for Wavelength-Dependent [4+4] Photocycloadditions". Chemistry – A European Journal. 26 (2): 478–484. doi:10.1002/chem.201903641. ISSN   1521-3765. PMID   31489724. S2CID   201844378.
  19. Irshadeen, Ishrath Mohamed; Walden, Sarah L.; Wegener, Martin; Truong, Vinh X.; Frisch, Hendrik; Blinco, James P.; Barner-Kowollik, Christopher (22 December 2021). "Action Plots in Action: In-Depth Insights into Photochemical Reactivity". Journal of the American Chemical Society. 143 (50): 21113–21126. doi:10.1021/jacs.1c09419. ISSN   0002-7863. PMID   34859671. S2CID   244880552.
  20. Walden, Sarah L.; Carroll, Joshua A.; Unterreiner, Andreas-Neil; Barner-Kowollik, Christopher (8 November 2023). "Photochemical Action Plots Reveal the Fundamental Mismatch Between Absorptivity and Photochemical Reactivity". Advanced Science. 11 (3): e2306014. doi: 10.1002/advs.202306014 . ISSN   2198-3844. PMC   10797470 . PMID   37937391.
  21. Frisch, Hendrik; Menzel, Jan P.; Blößer, Fabian R.; Marschner, David; Mundsinger, Kai; Barner-Kowollik, Christopher (2 July 2018). "Photochemistry in Confined Environments for Single Chain Nanoparticle Design". Journal of the American Chemical Society. 140 (30): 9551–9557. doi:10.1021/jacs.8b04531. ISSN   0002-7863. PMID   29965750. S2CID   207191317.
  22. Hiltebrandt, Kai; Pauloehrl, Thomas; Blinco, James P.; Linkert, Katharina; Börner, Hans G.; Barner-Kowollik, Christopher (23 January 2015). "λ-Orthogonal Pericyclic Macromolecular Photoligation". Angewandte Chemie International Edition. 54 (9): 2838–2843. doi:10.1002/anie.201410789. ISSN   1433-7851. PMID   25620295.
  23. Houck, Hannes A.; Blasco, Eva; Du Prez, Filip E.; Barner-Kowollik, Christopher (7 August 2019). "Light-Stabilized Dynamic Materials". Journal of the American Chemical Society. 141 (31): 12329–12337. doi:10.1021/jacs.9b05092. ISSN   0002-7863. PMID   31240918.
  24. Mueller, Patrick; Zieger, Markus M.; Richter, Benjamin; Quick, Alexander S.; Fischer, Joachim; Mueller, Jonathan B.; Zhou, Lu; Nienhaus, Gerd Ulrich; Bastmeyer, Martin (8 June 2017). "Molecular Switch for Sub-Diffraction Laser Lithography by Photoenol Intermediate-State Cis–Trans Isomerization". ACS Nano. 11 (6): 6396–6403. doi:10.1021/acsnano.7b02820. ISSN   1936-0851. PMID   28582617.
  25. Zieger, Markus M.; Mueller, Patrick; Quick, Alexander S.; Wegener, Martin; Barner-Kowollik, Christopher (13 April 2017). "Cleaving Direct-Laser-Written Microstructures on Demand". Angewandte Chemie International Edition. 56 (20): 5625–5629. doi:10.1002/anie.201701593. ISSN   1433-7851. PMID   28407401.
  26. Barner-Kowollik, Christopher; Bastmeyer, Martin; Blasco, Eva; Delaittre, Guillaume; Müller, Patrick; Richter, Benjamin; Wegener, Martin (15 November 2017). "3D Laser Micro- and Nanoprinting: Challenges for Chemistry". Angewandte Chemie International Edition. 56 (50): 15828–15845. doi:10.1002/anie.201704695. ISSN   1433-7851. PMID   28580704.
  27. Gräfe, David; Wickberg, Andreas; Zieger, Markus Michael; Wegener, Martin; Blasco, Eva; Barner-Kowollik, Christopher (17 July 2018). "Adding chemically selective subtraction to multi-material 3D additive manufacturing". Nature Communications. 9 (1): 2788. Bibcode:2018NatCo...9.2788G. doi:10.1038/s41467-018-05234-0. ISSN   2041-1723. PMC   6050325 . PMID   30018325.
  28. Richter, Benjamin; Hahn, Vincent; Bertels, Sarah; Claus, Tanja K.; Wegener, Martin; Delaittre, Guillaume; Barner-Kowollik, Christopher; Bastmeyer, Martin (2017). "Guiding Cell Attachment in 3D Microscaffolds Selectively Functionalized with Two Distinct Adhesion Proteins". Advanced Materials. 29 (5): 1604342. Bibcode:2017AdM....2904342R. doi:10.1002/adma.201604342. ISSN   1521-4095. PMID   27882610. S2CID   12683794.
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