Cyclobutrifluram

Last updated

Cyclobutrifluram
Cyclobutrifluram.png
Names
Preferred IUPAC name
N-[(1R,2R)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)pyridine-3-carboxamide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.307.361 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 942-593-7
PubChem CID
UNII
  • InChI=1S/C17H13Cl2F3N2O/c18-9-3-4-10(13(19)8-9)11-5-6-14(11)24-16(25)12-2-1-7-23-15(12)17(20,21)22/h1-4,7-8,11,14H,5-6H2,(H,24,25)/t11-,14-/m1/s1
    Key: GBFKIHJZPMECCF-BXUZGUMPSA-N
  • C1C[C@H]([C@H]1C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=C(N=CC=C3)C(F)(F)F
Properties
C17H13Cl2F3N2O
Molar mass 389.20 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cyclobutrifluram is a chemical compound which acts as a nematicide and also shows antifungal effects against Fusarium species. It was first approved for agricultural use in 2025. [1] Concerns have been raised about cyclobutrifluram and several other recently approved pesticides due to their high persistence in the environment and metabolism to polyfluoroalkyl substances (PFAS) such as trifluoroacetic acid. [2]

References

  1. ↑ Flemming A, Guest M, Luksch T, O'Sullivan A, Screpanti C, Dumeunier R, et al. (May 2025). "The discovery of Cyclobutrifluram, a new molecule with powerful activity against nematodes and diseases". Pest Management Science. 81 (5): 2480–2490. Bibcode:2025PMSci..81.2480F. doi:10.1002/ps.8730. PMID   40007473.
  2. ↑ Erickson BE (14 July 2025). "4 new pesticides ignite debate over PFAS definition". Chemical and Engineering News. 103 (17).
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