DIP2A

DIP2A
Identifiers
Aliases	DIP2A , C21orf106, DIP2, disco interacting protein 2 homolog A
External IDs	OMIM: 607711 MGI: 2385920 HomoloGene: 41012 GeneCards: DIP2A
Gene location (Human) Chr. Chromosome 21 (human) [1] Band 21q22.3 Start 46,458,891 bp [1] End 46,570,015 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10 C1|10 38.76 cM Start 76,095,263 bp [2] End 76,181,125 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in visceral pleura parietal pleura tibia cardia ventral tegmental area renal medulla inferior ganglion of vagus nerve nipple sperm endothelial cell Top expressed in substantia nigra otolith organ utricle iris anterior horn of spinal cord trigeminal ganglion pontine nuclei ciliary body ventral tegmental area conjunctival fornix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function catalytic activity protein binding Cellular component nucleus cell surface Biological process multicellular organism development negative regulation of gene expression metabolism regulation of apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23181 64451 Ensembl ENSG00000160305 ENSMUSG00000020231 UniProt Q14689 Q8BWT5 RefSeq (mRNA) NM_001146114 NM_001146115 NM_001146116 NM_015151 NM_206889 NM_206890 NM_206891 NM_001353942 NM_001353943 NM_001353944 NM_001081419 RefSeq (protein) NP_001139587 NP_001139588 NP_055966 NP_996772 NP_996773 NP_996774 NP_001340871 NP_001340872 NP_001340873 NP_001074888 Location (UCSC) Chr 21: 46.46 – 46.57 Mb Chr 10: 76.1 – 76.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Disco-interacting protein 2 homolog A is a protein that in humans is encoded by the DIP2A gene. ^[5]

See also

• DIP2B
• DIP2C

References

1. GRCh38: Ensembl release 89: ENSG00000160305 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020231 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)".

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi: 10.1093/dnares/3.1.17 . PMID   8724849.
• Yu G, Zerucha T, Ekker M, Rubenstein JL (2002). "Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins". Brain Res. Dev. Brain Res. 130 (2): 217–30. doi:10.1016/S0165-3806(01)00239-5. PMID   11675124.
• Wang Z, Tseng CP, Pong RC, et al. (2002). "The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2". J. Biol. Chem. 277 (15): 12622–31. doi: 10.1074/jbc.M110568200 . PMID   11812785.
• Gardiner K, Slavov D, Bechtel L, Davisson M (2002). "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis". Genomics. 79 (6): 833–43. doi:10.1006/geno.2002.6782. PMID   12036298.
• Mukhopadhyay M, Pelka P, DeSousa D, et al. (2002). "Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog". Gene. 293 (1–2): 59–65. doi:10.1016/S0378-1119(02)00694-7. PMID   12137943.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Casadei R, Strippoli P, D'Addabbo P, et al. (2004). "mRNA 5' region sequence incompleteness: a potential source of systematic errors in translation initiation codon assignment in human mRNAs". Gene. 321: 185–93. doi:10.1016/S0378-1119(03)00835-7. PMID   14637006.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Winnepenninckx B, Debacker K, Ramsay J, et al. (2007). "CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1". Am. J. Hum. Genet. 80 (2): 221–31. doi:10.1086/510800. PMC   1785358 . PMID   17236128.