DIP2B

Last updated
DIP2B
Identifiers
Aliases DIP2B , disco interacting protein 2 homolog B
External IDs OMIM: 611379 MGI: 2145977 HomoloGene: 72227 GeneCards: DIP2B
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020849
NM_173602

NM_001159361
NM_172819

RefSeq (protein)

NP_775873

NP_001152833
NP_766407
NP_001389830

Location (UCSC) Chr 12: 50.5 – 50.75 Mb Chr 15: 99.94 – 100.12 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

DIP2 disco-interacting protein 2 homolog B (Drosophila) is a protein that in humans is encoded by the DIP2B gene. [5] A member of the disco-interacting protein homolog 2 protein family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence of these sites suggests that DIP2B may participate in DNA methylation. This gene is located near a folate-sensitive fragile site. [5] [6]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000066084 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000023026 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "DIP2 disco-interacting protein 2 homolog B (Drosophila)" . Retrieved 2011-12-05.
  6. Winnepenninckx B, Debacker K, Ramsay J, Smeets D, Smits A, FitzPatrick DR, et al. (February 2007). "CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1". American Journal of Human Genetics. 80 (2): 221–231. doi:10.1086/510800. PMC   1785358 . PMID   17236128.

Further reading