DYNC1I1

Last updated
DYNC1I1
Identifiers
Aliases DYNC1I1 , dynein, cytoplasmic 1, intermediate chain 1, DNCI1, DNCIC1, dynein cytoplasmic 1 intermediate chain 1
External IDs OMIM: 603772; MGI: 107743; HomoloGene: 68398; GeneCards: DYNC1I1; OMA:DYNC1I1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135556
NM_001135557
NM_001278421
NM_001278422
NM_004411

Contents

NM_001191023
NM_001191025
NM_001191026
NM_001191027
NM_010063

RefSeq (protein)

NP_001129028
NP_001129029
NP_001265350
NP_001265351
NP_004402

NP_001177952
NP_001177954
NP_001177955
NP_001177956
NP_034193

Location (UCSC) Chr 7: 95.77 – 96.11 Mb Chr 6: 5.73 – 6.03 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene. [5] [6] [7]

In melanocytic cells DYNC1I1 gene expression may be regulated by MITF. [8]

Interactions

DYNC1I1 has been shown to interact with DYNLL1. [9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000158560 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029757 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Crackower MA, Sinasac DS, Xia J, Motoyama J, Prochazka M, Rommens JM, Scherer SW, Tsui LC (May 1999). "Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human". Genomics. 55 (3): 257–67. doi:10.1006/geno.1998.5665. PMID   10049579.
  6. Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC   2171247 . PMID   16260502.
  7. "Entrez Gene: DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1".
  8. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi: 10.1111/j.1755-148X.2008.00505.x . PMID   19067971. S2CID   24698373.
  9. Diefenbach, Russell J; Diefenbach Eve; Douglas Mark W; Cunningham Anthony L (Dec 2002). "The heavy chain of conventional kinesin interacts with the SNARE proteins SNAP25 and SNAP23". Biochemistry. 41 (50). United States: 14906–15. doi:10.1021/bi026417u. ISSN   0006-2960. PMID   12475239.

Further reading