Dextranomer

Dextranomer

Clinical data
Trade names	Debrisan
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
ATC code	D03AX02 ( WHO )
Identifiers
IUPAC name Dextran, 2,3-dihydroxypropyl 2-hydroxy-1,3-propanediyl ethers
CAS Number	56087-11-7  N
PubChem SID	214362
ChemSpider	none
UNII	30KXI0TVD3
ECHA InfoCard	100.128.106
NY  (what is this?)    (verify)

Dextranomer (trade name Debrisan, Exudex ^[1] ) is a cicatrizant used in dressings for wound healing, ^[2] and in pharmaceutical products to treat fecal incontinence. ^[3] It consists of dextran polymer chains cross-linked into a three-dimensional network. ^[4]

Solesta

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI). ^[5] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).

References

1. "Establishment Registration & Device Listing". Archived from the original on February 7, 2017.
2. Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33. PMID   2413198.
3. "Solesta Gel Approved for Fecal Incontinence - Drugs.com MedNews".
4. Solesta Package Insert
5. Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID   22845415. S2CID   6499631.

External links

• dextranomer at the U.S. National Library of Medicine Medical Subject Headings (MeSH)