Diazaborine B

Diazaborine B
Names
	Preferred IUPAC name 2-(4-Methylbenzene-1-sulfonyl)-2,3,1-benzodiazaborinin-1(2H)-ol
Identifiers
CAS Number	22959-81-5 ;
3D model (JSmol)	Interactive image ;
ChEBI	CHEBI:83945 ;
ChEMBL	ChEMBL168634 ;
ChemSpider	422598 ;
DrugBank	DB08265 ;
PubChem CID	481709 ;
UNII	YEB3W2L5P3 ;
CompTox Dashboard (EPA)	DTXSID201148398 ;
	InChI InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3;
	SMILES O=S(=O)(N2/N=C\c1c(cccc1)B2O)c3ccc(cc3)C;
Properties
Chemical formula	C14H13BN2O3S
Molar mass	300.14 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated August 26, 2025

Diazaborine B is a chemical compound that inhibits maturation of rRNAs for the large ribosomal subunit.^[1]

References

↑ Pertschy, B.; Zisser, G.; Schein, H.; Koffel, R.; Rauch, G.; Grillitsch, K.; Morgenstern, C.; Durchschlag, M.; Hogenauer, G. (2004). "Diazaborine Treatment of Yeast Cells Inhibits Maturation of the 60S Ribosomal Subunit". Molecular and Cellular Biology. 24 (14): 6476–6487. doi:10.1128/MCB.24.14.6476-6487.2004. PMC 434233 . PMID 15226447.

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[1] Pertschy, B.; Zisser, G.; Schein, H.; Koffel, R.; Rauch, G.; Grillitsch, K.; Morgenstern, C.; Durchschlag, M.; Hogenauer, G. (2004). "Diazaborine Treatment of Yeast Cells Inhibits Maturation of the 60S Ribosomal Subunit". Molecular and Cellular Biology. 24 (14): 6476–6487. doi:10.1128/MCB.24.14.6476-6487.2004. PMC 434233 . PMID 15226447.

[1]

Names


Preferred IUPAC name 2-(4-Methylbenzene-1-sulfonyl)-2,3,1-benzodiazaborinin-1(2H)-ol
Identifiers
CAS Number	22959-81-5 ^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:83945 ^Y
ChEMBL	ChEMBL168634
ChemSpider	422598
DrugBank	DB08265
PubChem CID	481709
UNII	YEB3W2L5P3 ^Y
CompTox Dashboard (EPA)	DTXSID201148398
InChI InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3
SMILES O=S(=O)(N2/N=C\c1c(cccc1)B2O)c3ccc(cc3)C
Properties
Chemical formula	C₁₄H₁₃BN₂O₃S
Molar mass	300.14 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references