 | |
| Names | |
|---|---|
| IUPAC name 5,6-Dioxo-2,3,5,6-tetrahydro-1H-indole-2-carboxylic acid | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| MeSH | dopachrome |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
| |
| |
| Properties | |
| C9H7NO4 | |
| Molar mass | 193.158 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Dopachrome is a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin. [1] It may tautomerise to form DHICA.
Iosif Vissarionovich Stalin, commonly known as Joseph Stalin, was a Georgian revolutionary and Soviet political leader who led the Soviet Union from 1924 until his death in 1953. He held power as General Secretary of the Communist Party of the Soviet Union (1922–1952) and Chairman of the Council of Ministers of the Soviet Union (1941–1953). Initially governing the country as part of a collective leadership, he consolidated power to become a dictator by the 1930s. Ideologically adhering to the Leninist interpretation of Marxism, he formalised these ideas as Marxism–Leninism, while his own policies are called Stalinism.
Sir Winston Leonard Spencer Churchill was a British statesman, soldier, and writer who served as Prime Minister of the United Kingdom twice, from 1940 to 1945 during the Second World War, and again from 1951 to 1955. Apart from two years between 1922 and 1924, he was a Member of Parliament (MP) from 1900 to 1964 and represented a total of five constituencies. Ideologically an adherent to economic liberalism and imperialism, he was for most of his career a member of the Conservative Party, which he led from 1940 to 1955. He was a member of the Liberal Party from 1904 to 1924.
Melanin is a broad term for a group of natural pigments found in most organisms. The melanin pigments are produced in a specialized group of cells known as melanocytes.
DCT may refer to:
The Gulf War was an armed conflict between Iraq and a 42-country coalition led by the United States. The coalition's efforts against Iraq were carried out in two key phases: Operation Desert Shield, which marked the military buildup from August 1990 to January 1991; and Operation Desert Storm, which began with the aerial bombing campaign against Iraq on 17 January 1991 and came to a close with the American-led Liberation of Kuwait on 28 February 1991.
Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin.
DCF may refer to:
Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin. The enzyme is mainly involved in two distinct reactions of melanin synthesis otherwise known as the Raper Mason pathway. Firstly, the hydroxylation of a monophenol and secondly, the conversion of an o-diphenol to the corresponding o-quinone. o-Quinone undergoes several reactions to eventually form melanin. Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesized in the skin melanocytes. In humans, the tyrosinase enzyme is encoded by the TYR gene.
Macrophage migration inhibitory factor (MIF), also known as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase is a protein that in humans is encoded by the MIF gene. MIF is an important regulator of innate immunity. The MIF protein superfamily also includes a second member with functionally related properties, the D-dopachrome tautomerase (D-DT). CD74 is a surface receptor for MIF.
In enzymology, a L-dopachrome isomerase is an enzyme that catalyzes the chemical reaction
The enzyme D-dopachrome decarboxylase (EC 4.1.1.84) catalyzes the chemical reaction
Dopachrome tautomerase , also known as DCT, is a human gene. Its expression is regulated by the microphthalmia-associated transcription factor (MITF).
Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene.
D-dopachrome decarboxylase is an enzyme that in humans is encoded by the DDT gene.
Genghis Khan, also known as Chinggis Khan, was the founder and first khagan of the Mongol Empire, which later became the largest contiguous land empire in history. Having spent the majority of his life uniting the Mongol tribes, he launched a series of military campaigns that conquered large parts of China and Central Asia.
Ganesha, also spelled Ganesh, and also known as Ganapati, Vinayaka, and Pillaiyar, is one of the best-known and most worshipped deities in the Hindu pantheon and is the Supreme God in the Ganapatya sect. His depictions are found throughout India. Hindu denominations worship him regardless of affiliations. Devotion to Ganesha is widely diffused and extends to Jains and Buddhists and beyond India.
Indole-5,6-quinone is an indolequinone, a chemical compound found in the oxidative browning reaction of fruits like bananas where it is mediated by the tyrosinase type polyphenol oxidase from tyrosine and catecholamines leading to the formation of catechol melanin. Like many quinones it can undergo redox reactions via the corresponding 5,6-dihydroxyindole.
Macrophage migration inhibitory factor domain is an evolutionary conserved protein domain.
DHICA is an intermediate in the biosynthesis of melanin. Tautomerization of DHICA forms dopachrome.
The molecular formula C9H7NO4 (molar mass: 193.16 g/mol, exact mass: 193.0375 u) may refer to:
