ERG28

ERG28
Identifiers
Aliases	ERG28 , NET51, C14orf1, chromosome 14 open reading frame 1, ergosterol biosynthesis 28 homolog
External IDs	OMIM: 604576; MGI: 1915571; HomoloGene: 38284; GeneCards: ERG28; OMA:ERG28 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q24.3 Start 75,649,791 bp [1] End 75,660,876 bp [1]
Gene location (Mouse) Chr. Chromosome 12 (mouse) [2] Band 12|12 D2 Start 85,862,222 bp [2] End 85,871,324 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte nipple human penis gingival epithelium left testis right testis corpus epididymis retinal pigment epithelium secondary oocyte right lobe of liver Top expressed in genital tubercle zygote tail of embryo yolk sac dentate gyrus of hippocampal formation granule cell left lobe of liver ventricular zone secondary oocyte lip right kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-macromolecule adaptor activity molecular function Cellular component integral component of membrane transport vesicle endoplasmic reticulum membrane endoplasmic reticulum membrane Biological process steroid metabolic process sterol biosynthetic process lipid metabolism steroid biosynthetic process ergosterol biosynthetic process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11161 58520 Ensembl ENSG00000133935 ENSMUSG00000021252 UniProt Q9UKR5 Q9ERY9 RefSeq (mRNA) NM_007176 NM_021446 NM_001360451 NM_001360813 RefSeq (protein) NP_009107 NP_067421 NP_001347380 NP_001347742 Location (UCSC) Chr 14: 75.65 – 75.66 Mb Chr 12: 85.86 – 85.87 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ergosterol biosynthetic protein 28 is a protein that in humans is encoded by the ERG28 gene. ^{[5] [6] [7] [8]}

References

1. GRCh38: Ensembl release 89: ENSG00000133935 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021252 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Veitia RA, Ottolenghi C, Bissery MC, Fellous A (Oct 1999). "A novel human gene, encoding a potential membrane protein conserved from yeast to man, is strongly expressed in testis and cancer cell lines". Cytogenetics and Cell Genetics. 85 (3–4): 217–20. doi:10.1159/000015296. PMID   10449901. S2CID   45886286.
6. Schirmer EC, Florens L, Guan T, Yates JR, Gerace L (Sep 2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. Bibcode:2003Sci...301.1380S. doi:10.1126/science.1088176. PMID   12958361. S2CID   23832536.
7. Gachotte D, Eckstein J, Barbuch R, Hughes T, Roberts C, Bard M (Jan 2001). "A novel gene conserved from yeast to humans is involved in sterol biosynthesis". Journal of Lipid Research. 42 (1): 150–4. doi: 10.1016/S0022-2275(20)32347-6 . PMID   11160377.
8. "Entrez Gene: C14orf1 chromosome 14 open reading frame 1".

External links

• Human C14orf1 genome location and C14orf1 gene details page in the UCSC Genome Browser .

Further reading

• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl: 11858/00-001M-0000-0010-8592-0 . PMID   16169070. S2CID   8235923.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Oct 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
• Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (Aug 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi: 10.1073/pnas.160270997 . PMC   16901 . PMID   10931946.