Elizabeth New

Last updated

Elizabeth New
Born
Elizabeth Joy New

1984 (age 3940)
Alma mater University of Sydney
Durham University
Awards Eureka Prize, 2018
Scientific career
Institutions University of California, Berkeley
University of Sydney
Thesis Understanding the cellular behaviour of the luminescent lanthanide complexes  (2009)
Doctoral advisor David Parker
Website sydney.edu.au/science/people/elizabeth.new.php

Elizabeth Joy New AM SFHEA FRSC FRACI FRSN (born 1984) is an Australian chemist and Professor of the School of Chemistry, University of Sydney. She won the 2018 Australian Museum 3M Eureka Prize.

Contents

Early life and education

New was born in Sydney in 1984. She represented Australia at the International Chemistry Olympiad in 2000 and 2001, winning bronze and gold medals respectively, [1] and graduated from James Ruse Agricultural High School with a UAI of 100. [2] She earned a bachelor's degree in chemistry at the University of Sydney in 2005, where she completed her master's degree in 2006 with Professor Trevor Hambley. [3] During her graduate studies she worked on fluorescent tags to monitor the cellular uptake and metabolism of anti-tumor complexes. [4] New completed her doctoral studies at Durham University working with David Parker, graduating in 2010. [5] [3] [6] [7] [8] Her work looked at the cellular behaviour of lanthanide complexes. [4]

Research and career

She was appointed a Royal Commission for the Exhibition of 1851 Research Fellow at the University of California, Berkeley in 2010. [3] She worked with Christopher Chang on fluorescent sensors for copper. [9] She was an Australian Research Council Discovery Early Career Research Fellow from 2012-2014, [3] and held a Westpac Research Fellowship from 2016-2019. [10] New's group developed reversible fluorescent sensors for cellular redox environments. [11] She provided the first examples of reversible ratiometric cytoplasmic sensing and mitochondrial sensing. [12] [13] Her group has developed cobalt complexes for contrast agents in magnetic resonance imaging. [9] [14] The complexes can be used to monitor oxidative stress. [3] They have also worked on the development of fluorescent sensor arrays for biological and analytical applications. [15] [16]

New was made a lecturer in 2015 and a senior lecturer in 2016. [3] In 2017 she received the ChemComm Emerging Investigator. [9] She was appointed Associate Professor in 2018 [3] and Professor in 2021. [17]

Awards

Related Research Articles

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References

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  4. 1 2 3 "Dalton Young Researchers Award 2011 Winner". www.rsc.org. Retrieved 31 August 2018.
  5. New, Elizabeth Joy (2009). Understanding the cellular behaviour of the luminescent lanthanide complexes (PhD thesis). Durham University. OCLC   757073288. EThOS   uk.bl.ethos.503234.
  6. New, Elizabeth J.; Parker, David (2009). "The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation". Organic & Biomolecular Chemistry. 7 (5): 851–5. doi:10.1039/B822145F. ISSN   1477-0520. PMID   19225664.
  7. Montgomery, Craig P.; Murray, Benjamin S.; New, Elizabeth J.; Pal, Robert; Parker, David (21 July 2009). "Cell-Penetrating Metal Complex Optical Probes: Targeted and Responsive Systems Based on Lanthanide Luminescence". Accounts of Chemical Research. 42 (7): 925–937. doi:10.1021/ar800174z. ISSN   0001-4842. PMID   19191558.
  8. New, Elizabeth J.; Congreve, Aileen; Parker, David (2010). "Definition of the uptake mechanism and sub-cellular localisation profile of emissive lanthanide complexes as cellular optical probes". Chemical Science. 1 (1): 111. doi:10.1039/C0SC00105H. ISSN   2041-6520.
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  12. Kaur, Amandeep; Haghighatbin, Mohammad A.; Hogan, Conor F.; New, Elizabeth J. (2015). "A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry". Chemical Communications. 51 (52): 10510–10513. doi:10.1039/C5CC03394B. ISSN   1359-7345. PMID   26036917.
  13. Kaur, Amandeep; Brigden, Kurt W. L.; Cashman, Timothy F.; Fraser, Stuart T.; New, Elizabeth J. (2015). "Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells". Organic & Biomolecular Chemistry. 13 (24): 6686–6689. doi:10.1039/C5OB00928F. ISSN   1477-0520. PMID   26006184.
  14. Shen, Clara; Harris, Benjamin D. W.; Dawson, Lucy J.; Charles, Kellie A.; Hambley, Trevor W.; New, Elizabeth J. (2015). "Fluorescent sensing of monofunctional platinum species". Chemical Communications. 51 (29): 6312–6314. doi: 10.1039/C4CC08077G . ISSN   1359-7345. PMID   25760940.
  15. Bowyer, Amy A.; Mai, Anthony D.; Guo, Haobo; New, Elizabeth J. (16 May 2022). "A pH-Based Single-Sensor Array for Discriminating Metal Ions in Water". Chemistry – an Asian Journal. 17 (10): e202200204. doi:10.1002/asia.202200204. ISSN   1861-4728. PMC   9325419 . PMID   35388970.
  16. Mitchell, Linda; Shen, Clara; Timmins, Hannah C.; Park, Susanna B.; New, Elizabeth J. (26 March 2021). "A Versatile Fluorescent Sensor Array for Platinum Anticancer Drug Detection in Biological Fluids". ACS Sensors. 6 (3): 1261–1269. doi:10.1021/acssensors.0c02553. ISSN   2379-3694. PMID   33595280. S2CID   231946265.
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