Christopher Chang

Last updated

Christopher J. Chang
Born1974 (age 48–49)
Ames, Iowa
CitizenshipUnited States
Alma mater California Institute of Technology BS/MS (1997)
Massachusetts Institute of Technology PhD (2002)
Spouse Michelle Chang
AwardsACS Cope Scholar Award (2010)
Sackler Prize in Chemistry (2019)
Scientific career
Fields Chemistry
Institutions UC Berkeley
Thesis Small-molecule activation chemistry catalyzed by proton-coupled electron transfer  (2002)
Doctoral advisor Daniel G. Nocera
Other academic advisors Harry B. Gray, Jean-Pierre Sauvage, Stephen J. Lippard
Notable students Hemamala Karunadasa
Website www.cchem.berkeley.edu/cjcgrp/

Christopher J. Chang is a professor of chemistry and of molecular and cell biology at the University of California, Berkeley, where he holds the Class of 1942 Chair. [1] Chang is also a member of the Helen Wills Neuroscience Institute, a Howard Hughes Medical Institute investigator, adjunct professor of pharmaceutical chemistry at the University of California, San Francisco, and faculty scientist at the chemical sciences division of Lawrence Berkeley Lab. [1] [2] He is the recipient of several awards for his research in bioinorganic chemistry, molecular and chemical biology. [3]

Contents

His research interests include molecular imaging sensors for the study of redox biology [4] [5] and metals, [6] especially as applied to neuroscience and immunology, metal catalysts for renewable energy cycles, and green chemistry. [1]

Early life and education

Chang was born in 1974 in Ames, Iowa, and was raised in Indiana. [1] [7] He attended the California Institute of Technology for his undergraduate degree, where he studied chemistry. At Caltech, he worked with Harry B. Gray on the synthesis and characterization of metal salen complexes of manganese and vanadium, and nitrogen and oxygen transfer reactivity with these complexes, respectively. [8] [9] [10] Chang earned his BS and MS in chemistry in 1997, after which he worked in the laboratory of Jean-Pierre Sauvage at the Université Louis Pasteur as a Fulbright Fellow. In 1999, he moved to the Massachusetts Institute of Technology as a NSF/Merck Graduate Fellow. During his doctoral studies, Chang worked in the laboratory of Daniel G. Nocera. After earning his PhD in inorganic chemistry in 2002, Chang remained at MIT, working with Stephen J. Lippard as a Jane Coffin Childs Fellow.

Independent career

In 2004, Chang began his independent career as an assistant professor of chemistry at the University of California, Berkeley. He was promoted to associate professor in 2009, and full professor of chemistry in 2012, when he was also appointed professor of molecular and cell biology and co-director, chemical biology graduate program. [1]

Awards

Personal life

Christopher is married to his colleague in the department of chemistry, Michelle Chang. [7] [21]

Related Research Articles

<span class="mw-page-title-main">Ken Raymond</span> American inorganic chemist

Kenneth Norman Raymond is a bioinorganic and coordination chemist. He is Chancellor's Professor of Chemistry at the University of California, Berkeley, Professor of the Graduate School, the Director of the Seaborg Center in the Chemical Sciences Division at Lawrence Berkeley National Laboratory, and the President and Chairman of Lumiphore.

<span class="mw-page-title-main">Stephen J. Lippard</span> American chemist

Stephen James Lippard is the Arthur Amos Noyes Emeritus Professor of Chemistry at the Massachusetts Institute of Technology. He is considered one of the founders of bioinorganic chemistry, studying the interactions of nonliving substances such as metals with biological systems. He is also considered a founder of metalloneurochemistry, the study of metal ions and their effects in the brain and nervous system. He has done pioneering work in understanding protein structure and synthesis, the enzymatic functions of methane monooxygenase (MMO), and the mechanisms of cisplatin anticancer drugs. His work has applications for the treatment of cancer, for bioremediation of the environment, and for the development of synthetic methanol-based fuels.

Laura Lee Kiessling is an American chemist and the Novartis Professor of Chemistry at the Massachusetts Institute of Technology. Kiessling's research focuses on elucidating and exploiting interactions on the cell surface, especially those mediated by proteins binding to carbohydrates. Multivalent protein-carbohydrate interactions play roles in cell-cell recognition and signal transduction. Understanding and manipulating these interactions provides tools to study biological processes and design therapeutic treatments. Kiessling's interdisciplinary research combines organic synthesis, polymer chemistry, structural biology, and molecular and cell biology.

<span class="mw-page-title-main">Judith Klinman</span> American biochemist

Judith P. Klinman is an American chemist, biochemist, and molecular biologist known for her work on enzyme catalysis. She became the first female professor in the physical sciences at the University of California, Berkeley in 1978, where she is now Professor of the Graduate School and Chancellor's Professor. In 2012, she was awarded the National Medal of Science by President Barack Obama. She is a member of the National Academy of Sciences, American Academy of Arts and Sciences, American Association for the Advancement of Science, and the American Philosophical Society.

Gregory S. Girolami is the William H. and Janet G. Lycan Professor of Chemistry at the University of Illinois Urbana-Champaign. His research focuses on the synthesis, properties, and reactivity of new inorganic, organometallic, and solid state species. Girolami has been elected a fellow of the American Association for the Advancement of Science, the Royal Society of Chemistry, and the American Chemical Society.

<span class="mw-page-title-main">Abhik Ghosh</span> Indian chemist

Abhik Ghosh is an Indian inorganic chemist and materials scientist and a professor of chemistry at UiT – The Arctic University of Norway in Tromsø, Norway.

<span class="mw-page-title-main">Jillian Lee Dempsey</span> American inorganic chemist

Jillian Lee Dempsey is an American inorganic chemist and the Bowman and Gordon Gray Distinguished Term Professor at the University of North Carolina at Chapel Hill. Currently, her work focuses on proton-coupled electron transfer, charge transfer events, and quantum dots. She is the recipient of numerous awards for rising stars of chemistry, including most recently a 2016 Alfred P. Sloan Research Fellowship and a 2016 Air Force's Young Investigator Research Program (YIP).

<span class="mw-page-title-main">Rebecca Abergel</span> French inorganic chemist

Rebecca Abergel is a French inorganic chemist who specializes in the coordination chemistry between lanthanide and actinide complexes. Alongside the effects of heavy element exposure and contamination on different biological systems. Abergel is currently a faculty scientist and heavy element chemistry group leader at the chemical sciences division of Lawrence Berkeley National Laboratory in Berkeley, California. She is also assistant professor of nuclear engineering at University of California, Berkeley.

Christopher "Kit" Colin Cummins is an American chemist, currently the Henry Dreyfus Professor at the Massachusetts Institute of Technology. He has made contributions to the coordination chemistry of transition metal nitrides, phosphides, and carbides.

T. Don Tilley is a professor of chemistry at the University of California, Berkeley.

Jenny Yue-fon Yang is an American chemist. She is a Professor of chemistry at the University of California, Irvine where she leads a research group focused on inorganic chemistry, catalysis, and solar fuels.

<span class="mw-page-title-main">Dorothea Fiedler</span> German chemical biologist

Dorothea Fiedler is a chemical biologist and also the first female director of the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin, Germany.

Angelica M. Stacy is the associate vice provost for the faculty, and professor of chemistry, at University of California, Berkeley. Stacy was one of the first women to receive tenure in the college of chemistry at UC Berkeley.

Serena DeBeer is an American chemist. She is currently a W3-Professor and the director at the Max Planck Institute for Chemical Energy Conversion in Muelheim an der Ruhr, Germany, where she heads the Department of Inorganic Spectroscopy. Her expertise lies in the application and development of X-ray based spectroscopic methods as probes of electronic structure in biological and chemical catalysis.

<span class="mw-page-title-main">Hemamala Karunadasa</span> Chemist

Hemamala Indivari Karunadasa is an assistant professor of chemistry at Stanford University. She works on hybrid organic – inorganic materials, such as perovskites, for clean energy and large area lighting.

<span class="mw-page-title-main">Danna Freedman</span> American inorganic chemist

Danna Freedman is an American chemist and the Frederick George Keyes Professor of Chemistry at the Massachusetts Institute of Technology. Her group's research focuses on applying inorganic chemistry towards questions in physics, with an emphasis on quantum information science, materials with emergent properties, and magnetism. Freedman was awarded the 2019 ACS Award in Pure Chemistry and a MacArthur Fellowship in 2022.

<span class="mw-page-title-main">Marinella Mazzanti</span> Italian chemist

Marinella Mazzanti is an Italian inorganic chemist specialized in coordination chemistry. She is a professor at EPFL and the head of the group of Coordination Chemistry at EPFL's School of Basic Sciences.

Karsten Meyer is a German inorganic chemist and Chair of Inorganic and General Chemistry at the Friedrich-Alexander University of Erlangen-Nürnberg (FAU). His research involves the coordination chemistry of transition metals as well as uranium coordination chemistry, small molecule activation with these coordination complexes, and the synthesis of new chelating ligands. He is the 2017 recipient of the Elhuyar-Goldschmidt Award of the Spanish Royal Society of Chemistry, the Ludwig-Mond Award of the Royal Society of Chemistry, and the L.A. Chugaev Commemorative Medal of the Russian Academy of Sciences, among other awards. He also serves as an Associate Editor of the journal Organometallics since 2014.

Connie C. Lu is a Taiwanese-American inorganic chemist and a professor of chemistry at the University of Bonn. She was previously a professor of chemistry at the University of Minnesota, Twin Cities. Lu's research focuses on the synthesis of novel bimetallic coordination complexes, as well as metal-organic frameworks. These molecules and materials are investigated for the catalytic conversion of small molecules like as N2 and CO2 into value-added chemicals like ammonia and methanol. Lu is the recipient of multiple awards for her research, including the National Science Foundation CAREER Award and the Sloan Research Fellowship in 2013, and an Early Career Award from the University of Minnesota's Initiative for Renewable Energy and the Environment in 2010.

Karen Dale Williams Morse is a inorganic chemist. She was president of Western Washington University from 1993 until 2008, and was named the Bowman Distinguished Professor in 2014. She is an elected fellow of the American Association for the Advancement of Science.

References

  1. 1 2 3 4 5 "Christopher J. Chang | College of Chemistry". chemistry.berkeley.edu. Retrieved May 29, 2021.
  2. ↑ "Christopher J. Chang – Chemical Sciences Division Chemical Sciences Division". commons.lbl.gov. Retrieved May 29, 2021.
  3. ↑ "Chang Group – Homepage". Cchem.berkeley.edu. Retrieved May 6, 2015.
  4. ↑ Miller, Evan W.; Tulyathan, Orapim; Isacoff, Ehud Y.; Chang, Christopher J. (2007). "Molecular imaging of hydrogen peroxide produced for cell signaling : Abstract : Nature Chemical Biology". Nature Chemical Biology. 3 (5): 263–267. doi:10.1038/nchembio871. PMID   17401379.
  5. ↑ Dickinson, Bryan C.; Chang, Christopher J. (2008). "A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells". Journal of the American Chemical Society. 130 (30): 9638–9639. doi:10.1021/ja802355u. PMC   2810491 . PMID   18605728.
  6. ↑ Domaille, Dylan W.; Zeng, Li; Chang, Christopher J. (2010). "Visualizing Ascorbate-Triggered Release of Labile Copper within Living Cells using a Ratiometric Fluorescent Sensor". Journal of the American Chemical Society. 132 (4): 1194–1195. doi:10.1021/ja907778b. PMC   2819030 . PMID   20052977.
  7. 1 2 "Christopher Chang". American Chemical Society. Retrieved May 29, 2021.
  8. ↑ Chang, Christopher J.; Low, Donald W.; Gray, Harry B. (1997). "Reversible Nitrogen Atom Transfer between Nitridomanganese(V) and Manganese(III) Schiff-Base Complexes". Inorganic Chemistry. 36 (3): 270–271. doi:10.1021/ic961023a. ISSN   0020-1669.
  9. ↑ Chang, Christopher J.; Connick, William B.; Low, Donald W.; Day, Michael W.; Gray, Harry B. (1998). "Electronic Structures of Nitridomanganese(V) Complexes". Inorganic Chemistry. 37 (12): 3107–3110. doi:10.1021/ic970598k. ISSN   0020-1669.
  10. ↑ Chang, Christopher J.; Labinger, Jay A.; Gray, Harry B. (December 1, 1997). "Aerobic Epoxidation of Olefins Catalyzed by Electronegative Vanadyl Salen Complexes". Inorganic Chemistry. 36 (25): 5927–5930. doi:10.1021/ic970824q. ISSN   0020-1669. PMID   11670216.
  11. 1 2 3 4 5 6 7 8 9 10 "Faculty & Research | College of Chemistry". Chem.berkeley.edu. Retrieved May 6, 2015.
  12. ↑ "Chang, Christopher". The David and Lucile Packard Foundation. Retrieved May 29, 2021.
  13. ↑ "Hellman Fellows » Christopher Chang" . Retrieved May 29, 2021.
  14. ↑ "Innovator Under 35: Christopher Chang, 33". MIT Technology Review. Retrieved May 29, 2021.
  15. ↑ "2015 National Laureates". New York Academy of Sciences. Retrieved December 4, 2015.
  16. ↑ "Christopher J. Chang". American Academy of Arts & Sciences. Retrieved May 29, 2021.
  17. ↑ "Berkeley Professor Christopher J. Chang to stay at MPIMR after being awarded the Humboldt Research Award". www.mr.mpg.de. Retrieved May 29, 2021.
  18. ↑ "John Simon Guggenheim Foundation | Christopher J. Chang" . Retrieved May 29, 2021.
  19. ↑ Staff, Shylie Ati | (April 15, 2021). "4 UC Berkeley faculty receive Guggenheim Fellowship". The Daily Californian. Retrieved May 29, 2021.
  20. ↑ "Guggenheim Fellowship awarded to Christopher Chang | College of Chemistry". chemistry.berkeley.edu. Retrieved May 29, 2021.
  21. ↑ "National magazines tout two chemists and two astronomers as top innovators in their fields", UC Berkeley News, August 22, 2008 (retrieved December 12, 2014)
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.