Epomediol

Epomediol

Clinical data
Other names	1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol
ATC code	A05BA05 ( WHO )
Identifiers
IUPAC name (1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-6,7-diol
CAS Number	56084-15-2  Y
PubChem CID	115056
ChemSpider	102967
UNII	KFU4XSK3BK
CompTox Dashboard (EPA)	DTXSID70971470
Chemical and physical data
Formula	C10H18O3
Molar mass	186.251 g·mol−1
3D model (JSmol)	Interactive image
SMILES OC1CC2C(OC1(C)C(O)C2)(C)C

Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy. ^{[1] [2] [3]}

References

1. Gonzalez MC, Iglesias J, Tiribelli C, et al. (September 1992). "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol. 16 (1–2): 241–2. doi:10.1016/S0168-8278(05)80122-9. PMID   1484159.
2. Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am. 21 (4): 905–21. PMID   1478743.
3. Reyes H, Simon FR (August 1993). "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis. 13 (3): 289–301. doi:10.1055/s-2007-1007357. PMID   8235718.